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The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01521104
Recruitment Status : Completed
First Posted : January 30, 2012
Last Update Posted : January 30, 2012
Information provided by (Responsible Party):
Xiaobo Li, Shanghai Jiao Tong University School of Medicine

Brief Summary:
Magnification narrow band imaging (NBI) can make accurate evaluation in in predicting of invasive depth of colorectal neoplasia.

Condition or disease
Colorectal Neoplasms

Detailed Description:
NBI could be used in stratifying patients for endoscopic resection or surgery and got an accurate evaluation.

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Study Type : Observational
Actual Enrollment : 565 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Value of NBI in Stratifying Patients for Endoscopic Resection or Surgery
Study Start Date : January 2009
Actual Primary Completion Date : December 2010
Actual Study Completion Date : December 2010

Biospecimen Retention:   Samples Without DNA

All the lesions will be removed endoscopically or surgically and examined histologically by an independent gastrointestinal pathologist.

Histological diagnosis is determined according to the World Health Organization (WHO) criteria.Pedunculated lesions are categorized according to Haggitt's classification.

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
consecutive adult patients undergo colonoscopy and find out more than one lesion ≧ 6mm from Jan 2009 to Dec 2010

Inclusion Criteria:

  • Consecutive patients with more than one lesion ≧6mm

Exclusion Criteria:

  • Patients with chronic inflammatory bowel disease,
  • advanced cancer,
  • insufficient bowel preparation,
  • familial adenomatous polyposis (FAP)
  • Lesions ≦ 5mm and submucosal tumor (SMT).

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Responsible Party: Xiaobo Li, Shanghai Institute of Digestive Disease,Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University School of Medicine Identifier: NCT01521104    
Other Study ID Numbers: rjxhnk02
First Posted: January 30, 2012    Key Record Dates
Last Update Posted: January 30, 2012
Last Verified: January 2012
Keywords provided by Xiaobo Li, Shanghai Jiao Tong University School of Medicine:
narrow band imaging(NBI)
colorectal lesions
predicting histology
Additional relevant MeSH terms:
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Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases