Working… Menu

The Effect of Reducing Soreness in Marathon Runners

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01512082
Recruitment Status : Completed
First Posted : January 19, 2012
Last Update Posted : April 10, 2015
Information provided by (Responsible Party):
Northern Orthopaedic Division, Denmark

Brief Summary:
Delayed onset muscle soreness is defined as the sensition of pain and discomfort in skeletal muscles that occurs after eccentric muscle actions or strenuous exercise like a marathon.

Condition or disease Intervention/treatment Phase
Contracture of Muscle, Thigh Device: Pulsed electromagnetic field devices Not Applicable

Detailed Description:

There is a growing body of clinical evidence which shows that noninvasive, nonpharmacologic pulsed electromagnetic fields have many clinical effects. Pulsed electromagnetic fields have shown to reduce pain in different groups of patients. This concerns patients with osteoarthritis, rheumatoid arthritis, diabetic neuropathy, fibromyalgia, distal radius fractures, pelvic pain and postoperative patients.

A marathon is a muscular strain. Physiologic effects of a marathon involves muscular and connective tissue damage which initiates an inflammatory response as well as release of metabolic factors like lactate and free radicals, intracellular metabolites and by-products of proteolysis.

The objective of this study was to investigate the efficacy of pulsed electromagnetic fields compared to placebo in reducing delayed onset muscle soreness in marathon runners.

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 47 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
Official Title: The Effect of Pulsed Electromagnetic Field Therapy in Reducing Delayed Onset Muscle Soreness in Marathon Runners. A Double-blind Randomized Placebo-controlled Study.
Study Start Date : August 2011
Actual Primary Completion Date : May 2012
Actual Study Completion Date : May 2012

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: Active pulsed electromagnetic field Device: Pulsed electromagnetic field devices
Every person received two active devices. The devices emitted 2-ms bursts of 27.12 MHz sinusoidal waves repeating at 2 bursts/s. Peak magnetic field intensity was 0.05 G which induced an average electric field of 10 mV in the tissue with an effect of 7.3 mW/cm3.
Other Name: ActiPatch TM, Scandinavia ApS, Denmark

Sham Comparator: Non-active pulsed electromagnetic field Device: Pulsed electromagnetic field devices
Every persons received two sham pulsed electromagnetic field devices.
Other Name: ActiPatch TM, Scandinavia ApS, Denmark

Primary Outcome Measures :
  1. Thigh pain by walking [ Time Frame: 5 days ]

    Primary outcome of thigh pain during semi-squat during 5 days following the marathon showed a significantly lower pain among the active group compared to the placebo group.

    The outcome was thigh muscle pain measured on a 10 cm visual analog scale during a squat of 90 degrees three times a day; when they woke up, at 12 pm and 8 pm.

Secondary Outcome Measures :
  1. Registration of injuries and symptoms from the musculoskeletal system. [ Time Frame: 5 days ]
    The group that received active pulsed electromagnetic field was running for a significant longer time the first day following the marathon.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Completion of a marathon
  • Age > 18 years

Exclusion Criteria:

- Unable to read and speak Danish

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01512082

Layout table for location information
Orthopaedic Surgery Research Unit, Aalborg University Hospital
Aalborg, Denmark, 9000
Sponsors and Collaborators
Northern Orthopaedic Division, Denmark
Layout table for investigator information
Principal Investigator: Sten Rasmussen, M.D. Northern Orthopaedic Division, Aalborg University Hospital, Denmark

Layout table for additonal information
Responsible Party: Northern Orthopaedic Division, Denmark Identifier: NCT01512082     History of Changes
Other Study ID Numbers: N-20110021
First Posted: January 19, 2012    Key Record Dates
Last Update Posted: April 10, 2015
Last Verified: April 2015
Keywords provided by Northern Orthopaedic Division, Denmark:
Delayed onset muscle soreness
Pulsed electromagnetic field
Additional relevant MeSH terms:
Layout table for MeSH terms
Joint Diseases
Musculoskeletal Diseases
Muscular Diseases