The Utility of PSADv (PSA Density Velocity) While on Dutasteride for Predicting Prostate Cancer Incidence and Grade and Stage (PSADv)
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ClinicalTrials.gov Identifier: NCT01484808
Recruitment Status : Unknown
Verified November 2011 by University Urological Associates Inc.. Recruitment status was: Not yet recruiting
This is a review of previously published data from a large prostate cancer prevention study known as REDUCE. It is the investigators intention to review whether prostate specific antigen (PSA) velocity (change over time) will predict the presence of prostate cancer and its grade and stage (severity).
Condition or disease
This is a review of previously published data from a large prostate cancer prevention study known as REDUCE that utilized a 5 ARI, dutasteride. It is the investigators intention to review whether PSA velocity (change over time) will predict the presence of prostate cancer and its grade and stage (severity) by two year biopsy. The investigator will review and compare data to a previously published study of similar design with finasteride.
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Layout table for eligibility information
Ages Eligible for Study:
50 Years to 74 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Men with PSA elevation (>=4), 50-74 years old with negative biopsy of the prostate at study entry
50-74 years old with elevated PSA (>=4) along with negative entry biopsy of the prostate who had a subsequent biopsy by 24 months.
Any positive biopsy of the prostate indicative of cancer upon entry