Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery
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ClinicalTrials.gov Identifier: NCT01461031 |
Recruitment Status : Unknown
Verified July 2012 by Young Eun Moon, The Catholic University of Korea.
Recruitment status was: Recruiting
First Posted : October 27, 2011
Last Update Posted : July 6, 2012
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Pain Orthognathic Surgery | Drug: nefopam Drug: normal saline (control) | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 40 participants |
Allocation: | Randomized |
Intervention Model: | Single Group Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Primary Purpose: | Prevention |
Official Title: | Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery |
Study Start Date : | October 2011 |
Estimated Primary Completion Date : | September 2012 |
Estimated Study Completion Date : | September 2012 |
- Drug: nefopam
nefopam infusion for postoperative 24 hours
- Drug: normal saline (control)
normal saline infusion for postoperative 24 hours
- pain score on the visual analogue scale [ Time Frame: after orthognathic surgery (up to postoperative 24 hours) ]

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Ages Eligible for Study: | 20 Years to 60 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- aged 20-60 years
- undergoing elective orthognathic surgery
Exclusion Criteria:
- pregnancy
- psychiatric disease
- hepatobiliary or renal disease
- monoamine oxidase inhibitor-taking patients

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01461031
Contact: Young Eun Moon, M.D. | 822-2258-6163 | momo0910@hanmail.net |
Korea, Republic of | |
Seoul St.Mary's Hospital | Recruiting |
Seoul, Seocho-gu, Korea, Republic of, 137-701 |
Responsible Party: | Young Eun Moon, Anesthesiology and Pain Medicine, Clinical Assitant Professor, The Catholic University of Korea |
ClinicalTrials.gov Identifier: | NCT01461031 |
Other Study ID Numbers: |
nefopam-orthognathic |
First Posted: | October 27, 2011 Key Record Dates |
Last Update Posted: | July 6, 2012 |
Last Verified: | July 2012 |
pain orthognathic |
Pain, Postoperative Postoperative Complications Pathologic Processes Pain Neurologic Manifestations Nefopam |
Analgesics, Non-Narcotic Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs |