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An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study (BIG3)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01460264
Recruitment Status : Enrolling by invitation
First Posted : October 26, 2011
Last Update Posted : September 18, 2019
Sponsor:
Information provided by (Responsible Party):
Region Skane

Study Description
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Brief Summary:
This is an observational study aiming to identify and validate biomarkers (including imaging and clinical descriptors) for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD) and lung cancer.

Condition or disease
Chronic Obstructive Pulmonary Disease Cardiovascular Diseases Lung Cancer

Study Design
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Study Type : Observational
Estimated Enrollment : 10000 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: BIG3 - An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study
Actual Study Start Date : October 16, 2013
Estimated Primary Completion Date : December 2020
Estimated Study Completion Date : December 2020

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Groups and Cohorts
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Group/Cohort
exposed
current daily smokers 100 cigarettes or more during lifetime
unexposed
current non-smokers


Outcome Measures
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Biospecimen Retention:   Samples With DNA
whole blood, serum

Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   45 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Community sample,residents in Skåne county Sweden.
Criteria

Inclusion Criteria:

  • 45-75 years
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01460264


Locations
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Sweden
Skåne University Hospital
Lund, Sweden, 221 85
Sponsors and Collaborators
Region Skane
Investigators
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Study Chair: Ulf Malmqvist, MD, PhD Skane University Hospital
Principal Investigator: David Erlinge, MD, PhD Skane University Hospital
Principal Investigator: Claes-Göran Löfdahl, MD, PhD Skane University Hospital
Principal Investigator: Maria Planck, MD, PhD Skane University Hospital
More Information
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Publications:

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Responsible Party: Region Skane
ClinicalTrials.gov Identifier: NCT01460264    
Other Study ID Numbers: BIG3-Region_Skane
First Posted: October 26, 2011    Key Record Dates
Last Update Posted: September 18, 2019
Last Verified: September 2019
Keywords provided by Region Skane:
Prospective Cohort Study
Respiratory Function Tests
Computed Tomography
Electrocardiography
Peripheral Arterial Disease
Additional relevant MeSH terms:
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Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Cardiovascular Diseases
Lung Diseases
Respiratory Tract Diseases