Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01450917|
Recruitment Status : Completed
First Posted : October 12, 2011
Last Update Posted : October 12, 2011
Diaphragmatic contraction is controlled by phrenic nerve which consists of anterior rami of 3rd- 5th cervical nerve roots. Usually, It can't be evaluated from history taking and physical examination. Thus the diaphragmatic elevation on chest radiograph is assumed to identify the phrenic nerve dysfunction. Normally, the right diaphragm is higher than the left side about 1.5 ± 0.9 centimeters or 0.5 ± 0.3 time of vertebral height. Although there are several methods to determine the diaphragmatic elevation from previous studies, the accuracy, reliability, intra and inter-observer variation are problem.
Neurotization is the effective procedure to restore upper extremity function in root avulsion type. Phrenic nerve is one of the common donor nerves which used for this procedure. But sometimes, concomitant injury of this nerve can occur. Therefore, the investigators established "Diaphragmatic height index (DHI)" from chest radiograph to use as the diagnostic test for phrenic nerve dysfunction.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||245 participants|
|Observational Model:||Case Control|
|Official Title:||Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction|
|Study Start Date :||September 2009|
|Actual Primary Completion Date :||October 2009|
|Actual Study Completion Date :||October 2009|
Brachial plexus injured patients with phrenic nerve dysfunction
Brachial plexus injured patients without phrenic nerve dysfunction
Non brachial plexus injured patients
- The cut-off point of DHI for diagnosis of phrenic nerve dysfunction [ Time Frame: upto 3 years ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01450917
|Principal Investigator:||Saichol Wongtrakul, MD||Mahidol University|