COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Adjunctive Local Application of Lidocaine During Scleral Buckling Under General Anesthesia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01417572
Recruitment Status : Unknown
Verified January 2010 by Isfahan University of Medical Sciences.
Recruitment status was:  Recruiting
First Posted : August 16, 2011
Last Update Posted : August 16, 2011
Information provided by:
Isfahan University of Medical Sciences

Brief Summary:
The purpose of this study is to evaluate the effect of topical lidocaine in scleral buckling surgery.

Condition or disease Intervention/treatment Phase
Retinal Detachment Drug: lidocaine Phase 4

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
Study Start Date : January 2010
Actual Primary Completion Date : August 2010
Estimated Study Completion Date : September 2011

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: lidocaine Drug: lidocaine
to evaluate the effect of lidocaine on oculocardiac reflex during the surgery

Primary Outcome Measures :
  1. intraoperative heart rate measurement [ Time Frame: 6 month ]
  2. decrease in pain and nausea,vomiting after surgery [ Time Frame: 6 month ]
  3. decrease in ocr after application of topical lidocaine [ Time Frame: 6 month ]
  4. postoperative nausea and vommitting [ Time Frame: 6 month ]
  5. postoperative pain [ Time Frame: 6 month ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   20 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Retinal detachment
  • Retinal tear less than 3 hour clock

Exclusion Criteria:

  • Vitreous hemorrhage
  • Proliferative vitreoretinopathy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01417572

Layout table for location contacts
Contact: Amin Masjedi, MD +983112211915

Layout table for location information
Iran, Islamic Republic of
Isfahan University of Medical Sciences Recruiting
Isfahan, Iran, Islamic Republic of, 7864329800
Contact: amin masjedi, MD    +983112211915   
Principal Investigator: Amin Masjedi, MD         
Sponsors and Collaborators
Isfahan University of Medical Sciences
Layout table for additonal information
Responsible Party: isfahan university of medical sciences Identifier: NCT01417572    
Other Study ID Numbers: 199
First Posted: August 16, 2011    Key Record Dates
Last Update Posted: August 16, 2011
Last Verified: January 2010
Additional relevant MeSH terms:
Layout table for MeSH terms
Retinal Detachment
Retinal Diseases
Eye Diseases
Anesthetics, Local
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Anti-Arrhythmia Agents
Voltage-Gated Sodium Channel Blockers
Sodium Channel Blockers
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action