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Per-Oral Endoscopic Myotomy (POEM)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01402518
Recruitment Status : Completed
First Posted : July 26, 2011
Last Update Posted : March 10, 2020
Information provided by (Responsible Party):
Santiago Horgan, University of California, San Diego

Brief Summary:
This is a prospective chart review/data collection study of the per oral endoscopic myotomy (POEM) procedure, that will include questionnaires administered throughout the study. Subjects enrolled will be those intending to have a POEM procedure. Data will be collected and reviewed through 12 months post-op.

Condition or disease Intervention/treatment
Achalasia Procedure: Per-oral enodscopic myotomy

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Study Type : Observational
Actual Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Observational Study of the Per-Oral Endoscopic Myotomy (POEM) Procedure
Study Start Date : November 2009
Actual Primary Completion Date : November 2019
Actual Study Completion Date : November 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Endoscopy

Group/Cohort Intervention/treatment
Per-oral endoscopic myotomy Procedure: Per-oral enodscopic myotomy
Other Name: POEM

Primary Outcome Measures :
  1. To evaluate the outcomes of the per-oral endoscopic myotomy (POEM) procedure for the treatment of achalasia [ Time Frame: 1 year ]

Secondary Outcome Measures :
  1. To assess the quality of life, pain, and complications of the POEM approach [ Time Frame: 1 year ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients between the ages of 18-75 who present in the UC San Diego Surgical Specialties clinic with the diagnosis of achalasia will be offered participation in this study.


  1. Diagnosis of achalasia
  2. Age 18-75
  3. Mentally competent to give informed consent
  4. Scheduled to undergo a POEM procedure


  1. Pregnant women
  2. Any prior surgical treatment for achalasia

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01402518

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United States, California
University of California, San Diego
San Diego, California, United States, 92103
Sponsors and Collaborators
University of California, San Diego
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Principal Investigator: Santiago Horgan, M.D., FACS UCSD
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Responsible Party: Santiago Horgan, Professor of Surgery, University of California, San Diego Identifier: NCT01402518    
Other Study ID Numbers: 091170, 150261
First Posted: July 26, 2011    Key Record Dates
Last Update Posted: March 10, 2020
Last Verified: April 2018
Keywords provided by Santiago Horgan, University of California, San Diego:
endoscopic myotomy
difficulty swallowing
Additional relevant MeSH terms:
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Esophageal Achalasia
Esophageal Motility Disorders
Deglutition Disorders
Esophageal Diseases
Gastrointestinal Diseases
Digestive System Diseases