Developing Methods for Completing Future Satiety Studies
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|ClinicalTrials.gov Identifier: NCT01379911|
Recruitment Status : Completed
First Posted : June 23, 2011
Last Update Posted : January 21, 2016
Satiety is defined as the inhibition of eating, as a consequence of fullness after consuming food. Being able to effectively measure satiety is an important concept that has implications in the treatment and prevention of overweight and obesity. Increasing post-meal satiety is recognized a useful strategy for weight management. Recently, the category of foods marketed as having satiating effects has seen significant growth and this trend is expected to continue. The purpose of this project is to develop and validate methods for assessing the degree of satiety induced by foods and natural health products using commercially available food products.
This trial will examine the effects of a commercially available yogurt (containing added protein and fibre) on self-reported satiety and hunger, as well as food intake in both controlled and uncontrolled settings.
|Condition or disease||Intervention/treatment||Phase|
|Lack of Satiety||Other: Yogurt||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Double (Participant, Investigator)|
|Primary Purpose:||Basic Science|
|Official Title:||Developing and Validating a Method for Satiety Studies|
|Study Start Date :||February 2013|
|Actual Primary Completion Date :||October 2015|
|Actual Study Completion Date :||October 2015|
Active Comparator: Yogurt with added inulin
Yogurt with 6g of added inulin
Placebo Comparator: Regular yogurt
Regular yogurt without added inulin
- Self-reported ratings of satiety [ Time Frame: Outcome measures will be assessed at fasting (0 min) and postprandially (every 30 min) for 3 hours. ]The study consists of two trial days (pre- and post home consumption) per study period, one for each of 2 yogurts. Each study visit involves a 4-hour stay at the HNRU. The pre-study visit will be followed by a 6-day yogurt self-administration period where participants will consume the assigned yogurt at breakfast. Thus, the acute satiety effects of the yogurts will be replicated in a controlled (laboratory) setting and evaluated over a 6-day period in an uncontrolled (home/lifestyle) environment.
- Food intake [ Time Frame: One week ]Study will include food and caloric intake over entire study day and for 6 days subsequent to initial study visit.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01379911
|Human Nutraceutical Research Unit, University of Guelph|
|Guelph, Ontario, Canada, N1G2W1|
|Principal Investigator:||Amanda J Wright, Ph.D.||University of Guelph|