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Selective Lasertrabeculoplasty and Ocular Hemodynamics in Glaucoma (SLT/OBF)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01363362
Recruitment Status : Completed
First Posted : June 1, 2011
Last Update Posted : December 18, 2012
Sponsor:
Information provided by (Responsible Party):
Dr. Karin Pillunat, Technische Universität Dresden

Brief Summary:
Selective Laser Trabeculoplasty (SLT) is known to reduce intraocular pressure in glaucoma patients. This study investigates, if there are changes in different ocular hemodynamic parameters prior and after SLT.

Condition or disease Intervention/treatment Phase
Glaucoma Procedure: Selective Laser Trabeculoplasty Not Applicable

Detailed Description:
Ocular blood flow, ocular pulse amplitude and ocular pulse volume are measured with the Blood Flow Analyzer (Paradigm Medical Industries, Inc.) prior and 3 month after SLT.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 150 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effect of Selective Lasertrabeculoplasty (SLT) on Ocular Hemodynamics in Glaucoma
Study Start Date : December 2010
Actual Primary Completion Date : August 2011
Actual Study Completion Date : August 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Glaucoma

Arm Intervention/treatment
Experimental: glaucoma patients
Glaucoma patients undergoing selective laser trabeculoplasty for further IOP reduction
Procedure: Selective Laser Trabeculoplasty
360° selective laser trabeculoplasty, 100 non-overlapping spots, energy 0,5-1,2 mJ
Other Name: Lasertrabeculoplasty




Primary Outcome Measures :
  1. Change in ocular hemodynamics after Selective Laser Trabeculoplasty (SLT) [ Time Frame: baseline and 3 month ]
    Pulsatile ocular blood flow, ocular pulse amplitude and ocular pulse volume are measured prior and 3 month after SLT with the Blood Flow Analyzer (Paradigm Medical Industries, Inc.)



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • glaucoma patient
  • over 18 years
  • needs further intraocular pressure regulation

Exclusion Criteria:

  • age under 18 years
  • debilitated
  • no glaucoma

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01363362


Locations
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Germany
University Eye Clinic Dresden
Dresden, Saxony, Germany, 01307
Sponsors and Collaborators
Technische Universität Dresden
Investigators
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Study Chair: Lutz E Pillunat, Prof. MD University Eye Clinic Dresden
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Responsible Party: Dr. Karin Pillunat, Principal Investigator, Technische Universität Dresden
ClinicalTrials.gov Identifier: NCT01363362    
Other Study ID Numbers: SLT/OBF_EK 398122010
First Posted: June 1, 2011    Key Record Dates
Last Update Posted: December 18, 2012
Last Verified: December 2012
Keywords provided by Dr. Karin Pillunat, Technische Universität Dresden:
Selective Laser Trabeculoplasty
pulsatile ocular blood flow
Additional relevant MeSH terms:
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Glaucoma
Ocular Hypertension
Eye Diseases