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A Study of Mood and Stress After Spinal Cord Injury

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01337908
Recruitment Status : Completed
First Posted : April 19, 2011
Last Update Posted : March 20, 2012
Wayne State University
Santa Clara Valley Health & Hospital System
University of Washington
Information provided by (Responsible Party):
Claire Z. Kalpakjian, University of Michigan

Brief Summary:
This is a study of factors, such as pain, family support, psychological history and alcohol/substance use, that may influence whether a person experiences depression after their spinal cord injury.

Condition or disease
Spinal Cord Injury Depression

Detailed Description:
The objective of this study is to examine the degree to which vulnerability factors are mediated by stress to increase risk for depression after SCI in a sample of adults who sustained their injuries after the age of 18 years. Participants will complete a written survey (about pain, daily activities, social support and life experiences) and a telephone interview that will provide information about these factors.

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Study Type : Observational
Actual Enrollment : 377 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: A Survey of Vulnerability Factors, Current Stress and Depression Risk in Spinal Cord Injury
Study Start Date : February 2009
Actual Primary Completion Date : September 2011
Actual Study Completion Date : September 2011

Resource links provided by the National Library of Medicine

Biospecimen Retention:   Samples With DNA
Saliva samples collected with Oragene kit.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   19 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Men and women with a traumatic spinal cord injury who are 18 years of age and older

Inclusion Criteria:

  • Have a spinal cord injury
  • Were age 16 years or older when injured
  • Sudden onset of symptoms

Exclusion Criteria:

  • Under 19 years old
  • Less than 1 year post-injury
  • had a non-traumatic injury

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01337908

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United States, California
Santa Clara Valley Medical Center
San Jose, California, United States, 95128
United States, Michigan
University of Michigan
Ann Arbor, Michigan, United States, 48108
Rehabilitation Institute of Michigan
Detroit, Michigan, United States, 48201
United States, Washington
University of Washington
Seattle, Washington, United States, 98104
Sponsors and Collaborators
University of Michigan
Wayne State University
Santa Clara Valley Health & Hospital System
University of Washington
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Responsible Party: Claire Z. Kalpakjian, Assistant Professor, University of Michigan Identifier: NCT01337908    
Other Study ID Numbers: H133G070020
First Posted: April 19, 2011    Key Record Dates
Last Update Posted: March 20, 2012
Last Verified: March 2012
Keywords provided by Claire Z. Kalpakjian, University of Michigan:
quality of life
Additional relevant MeSH terms:
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Spinal Cord Injuries
Depressive Disorder
Wounds and Injuries
Behavioral Symptoms
Mood Disorders
Mental Disorders
Spinal Cord Diseases
Central Nervous System Diseases
Nervous System Diseases
Trauma, Nervous System