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Genetic Polymorphism and Israeli Top-level Swimmers' Performance and Expertise

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01319032
Recruitment Status : Unknown
Verified March 2011 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : March 21, 2011
Last Update Posted : March 21, 2011
Wingate Institute
Information provided by:
Hillel Yaffe Medical Center

Brief Summary:
In a study conducted in our laboratory few years ago, we genotyped 22 genes in 2 athletic groups (endurance and sprinters) and in age and gender matched nonathletic controls. Few of these genes were found to be associated with athletic performance and area of specificity. Since then a few more genes have been found that are related to athletic performance, and we intend to study various genes related to 3 genetic cascade: genes associated with body fluid balance and homeostasis, genes associated with muscle strength, and genes associated with bioenergy. The results of this study compared with athletic level will provide deeper insight into the genetic mechanisms involved in performance.

Condition or disease Intervention/treatment
Genetic Polymorphism Connected to Top-level Swimmers Other: Extraction of whole blood

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Study Type : Observational
Estimated Enrollment : 200 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : April 2011
Estimated Primary Completion Date : December 2011
Estimated Study Completion Date : December 2012

Group/Cohort Intervention/treatment
I. Top-level swimmers Other: Extraction of whole blood
Extraction of DNA from whole blood

II. Control
Other swimmers
Other: Extraction of whole blood
Extraction of DNA from whole blood

Primary Outcome Measures :
  1. Identification of genes associated with swimming performance [ Time Frame: One year ]

Biospecimen Retention:   Samples With DNA
Whole blood

Information from the National Library of Medicine

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Ages Eligible for Study:   13 Years to 40 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Swimmers training at the Wingate Institute

Inclusion Criteria:

  • Top-level swimmers
  • Other swimmers

Exclusion Criteria:

  • All others

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01319032

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Contact: Sigal Ben Zaken, PhD 972-52-2209853

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Wingate Institute
Netanya, Israel
Principal Investigator: Sigal Ben Zaken, PhD         
Sponsors and Collaborators
Hillel Yaffe Medical Center
Wingate Institute
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Eias Kassem, MD, Hillel Yaffe Medical Center Identifier: NCT01319032    
Other Study ID Numbers: 0013-11-HYMC
First Posted: March 21, 2011    Key Record Dates
Last Update Posted: March 21, 2011
Last Verified: March 2011