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ClinicalTrials.gov Identifier: NCT01303185
Recruitment Status :
First Posted : February 24, 2011
Last Update Posted : December 12, 2014
Taipei Medical University WanFang Hospital
Information provided by (Responsible Party):
Ying-Yi Chiang, Taipei Medical University WanFang Hospital
The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.
Condition or disease
Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.
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Layout table for eligibility information
Ages Eligible for Study:
16 Years and older (Child, Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Psoriatic nail patients
Psoriatic nail refractory to other topical and systemic treatment therapy
≧ 16 years old
Patient with pregnancy
Patient with photo sensitivity
Patient with severe wound around finger nails or paronychia