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The Correlation Between Genetic Polymorphism, Platelet Activity, Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01255267
Recruitment Status : Unknown
Verified December 2010 by China Medical University Hospital.
Recruitment status was:  Recruiting
First Posted : December 7, 2010
Last Update Posted : December 7, 2010
Sponsor:
Information provided by:
China Medical University Hospital

Brief Summary:
In this study, we evaluate the acute coronary syndrome patients to see if there is correlation between platelet activity, genetic polymorphism (CYP2C19 and ABCB1), serum adipokines level, and Clopidogrel responsiveness.

Condition or disease
Acute Coronary Syndrome Chronic Coronary Artery Disease

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Study Type : Observational
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Correlation Between Genetic Polymorphism, Platelet Activity, , Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients

Resource links provided by the National Library of Medicine


Group/Cohort
Acute coronary syndrome patients
Chronic coronary artery disease patients
Healthy control




Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Acute coronary syndrome and chronic coronary artery diseae patients
Criteria

Inclusion Criteria:

  1. Age > 18 y/o
  2. Acute coronary syndrome patients
  3. Chronic coronary artery disease patients
  4. Healthy volunteers

Exclusion Criteria:

  1. Patient refusal
  2. Allergy to Clopidogrel
  3. Receive Gp IIb/IIIa inhibitor simultaneously
  4. Cancer history
  5. Severe renal and liver function impairment
  6. Coagulopathy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01255267


Contacts
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Contact: Yu-Chen Wang, MD 886-4-22052121 ext 2371 richard9250@yahoo.com.tw

Locations
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Taiwan
China Medical University Hospital Recruiting
Taichung, Taiwan
Contact: Yu-Chen Wang, MD    886-4-22052121 ext 2371    richard9250@yahoo.com.tw   
Sponsors and Collaborators
China Medical University Hospital
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ClinicalTrials.gov Identifier: NCT01255267    
Other Study ID Numbers: DMR99-IRB-041
First Posted: December 7, 2010    Key Record Dates
Last Update Posted: December 7, 2010
Last Verified: December 2010
Keywords provided by China Medical University Hospital:
Acute coronary syndrome and chronic coronary artery disease patients
Additional relevant MeSH terms:
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Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Acute Coronary Syndrome
Syndrome
Disease
Pathologic Processes
Heart Diseases
Cardiovascular Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases