The Sinonasal Outcome Test - 22, Validated for Danish Patients
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|ClinicalTrials.gov Identifier: NCT01254916|
Recruitment Status : Completed
First Posted : December 7, 2010
Last Update Posted : May 8, 2012
Introduction: Chronic rhinosinusitis (CRS) is a significant health problem increasing in both incidence and prevalence. It calls into attention consensus about diagnosing, assessing symptoms and treatment of patients with CRS. Therefore a validated Danish measure of health-related quality of life in sinonasal disease is needed.
Method: The Sinonasal Outcome measure 22 (SNOT-22) was translated into Danish and reproducibility was evaluated by test-retesting 40 patients with CRS. The statistical analyses used, were Pearson´s correlation coefficient, Cronbach´s alfa, Kappa and Bland-Altman´s Plot. Reproducibility was also tested looking at subscales within the SNOT-22.
Result: The results show good internal correlation with Cronbach´s alfa at 0.83 in the initial test and 0.92 in the retest. Pearson was 0.70 (p<0.001) revealing good correlation between the initial scores and the retests scores. Kappa was calculated for each item with a mean value of 0.61 showing substantial agreement. Paired t-test revealed no significant difference in the subscales.
Conclusion: The Danish version of SNOT-22 is recommended for Danish clinicians and researches as a patient-reported measure of outcome in sino-nasal disorders such as rhinosinusitis and nasal polyposis.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||44 participants|
|Official Title:||The Sinonasal Outcome Test - 22, Validated for Danish Patients|
|Study Start Date :||October 2008|
|Actual Primary Completion Date :||March 2009|
|Actual Study Completion Date :||March 2009|
|Patients with chronic rhinosinusitis|
- Reproducibility of Sinonasal Outcome test 22 [ Time Frame: From the time of fullfilling the first SNOT-22 to fullfilling the second SNOT-22 after 14 days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01254916
|Department of Otorhinolaryngology, Odense University Hopsital|
|Odense, Denmark, DK-5000|