Effect of Wheat Dextrin on Calcium and Magnesium Absorption (Benefiber)
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|ClinicalTrials.gov Identifier: NCT01230840|
Recruitment Status : Completed
First Posted : October 29, 2010
Last Update Posted : October 29, 2010
|Condition or disease||Intervention/treatment||Phase|
|Colonic Inertia||Dietary Supplement: wheat dextrin Dietary Supplement: placebo||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Effect of Wheat Dextrin on Calcium and Magnesium Absorption|
|Study Start Date :||October 2009|
|Actual Primary Completion Date :||June 2010|
|Actual Study Completion Date :||October 2010|
Placebo Comparator: placebo
Control cookies will contain no wheat dextrin and will be taken 3 times daily for 2 weeks.
Dietary Supplement: placebo
cookies not containing wheat dextrin will be taken 3 times a day for 2 weeks
Experimental: wheat dextrin
wheat dextrin (formulated according to the supporter's established method), will be baked in cookies providing three doses per day (≈5 gram of wheat dextrin in each dose)for 2 weeks.
Dietary Supplement: wheat dextrin
5 grams of wheat dextrin baked in cookies will be taken 3 times a day for 2 weeks
- Calcium Absorption [ Time Frame: within 2-4 weeks ]The calcium load to be tested will be 300 mg calcium from calcium and vitamin D fortified TropicanaTM orange juice extrinsically labeled with ≈3-7 μCi of 45Ca. The labeled orange juice will be ingested as part of a light meal, served as breakfast, after an overnight fast.
- Magnesium absorption [ Time Frame: within 2-4 weeks ]The magnesium load to be tested will be from calcium and vitamin D fortified TropicanaTM orange juice extrinsically labeled with 30 mg 26Mg. The labeled orange juice will be ingested as part of a light meal, served as breakfast, after an overnight fast.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01230840
|Principal Investigator:||Laura Armas, MD||Creighton University|