Resveratrol in Type2 Diabetes and Obesity
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|ClinicalTrials.gov Identifier: NCT01158417|
Recruitment Status : Unknown
Verified December 2012 by Paresh Dandona, MD, Kaleida Health.
Recruitment status was: Active, not recruiting
First Posted : July 8, 2010
Last Update Posted : December 18, 2012
|Condition or disease||Intervention/treatment||Phase|
|Type 2 Diabetes Obesity Insulin Resistance||Drug: Placebo Drug: Resveratrol 40 mg oral three times a day Drug: Resveratrol 500 mg oral once daily.||Phase 2 Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||102 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Effect of Resveratrol on Insulin Resistance and Inflammatory Mediators in Obese and Type 2 Diabetic Subjects|
|Study Start Date :||December 2008|
|Estimated Primary Completion Date :||April 2014|
|Estimated Study Completion Date :||August 2014|
Placebo Comparator: Placebo
Experimental: Resveratrol 40 mg oral three times a day
Drug: Resveratrol 40 mg oral three times a day
Experimental: resveratrol 500 mg oral once daily.
Drug: Resveratrol 500 mg oral once daily.
Resveratrol 500 mg oral once daily.
- NF-Kb [ Time Frame: 12 weeks ]To investigate the effect of resveratrol on ROS generation and the pro-inflammatory transcription factor NF-kB
- GLP-1 [ Time Frame: 12 weeks ]To see whether Resveratrol leads to a greater stimulation of the incretin system and secretion/release of GIP and GLP-1 when compared to that following placebo
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01158417
|United States, New York|
|115 Flint Road|
|Buffalo, New York, United States, 14221|
|Principal Investigator:||Paresh Dandona, MD||Kaleida Health|