Pressure Support During Chest Wall Compression
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|ClinicalTrials.gov Identifier: NCT01155648|
Recruitment Status : Completed
First Posted : July 2, 2010
Last Update Posted : July 2, 2010
|Condition or disease||Intervention/treatment||Phase|
|Respiration, Artificial Critical Care||Device: Chest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest. Device: Chest wall compression for ten minutes in chest||Not Applicable|
- After being placed in the supine position in bed, with head angle elevation at 30°, patients were randomized to:group 1 (G1): chest wall compression for ten minutes in chest or group 2 (G2): chest wall compression plus increase of 10 cmH2O in IP in PSV for ten minutes in chest.
- Clinical variables and APACHE II were registered.
- Parameters analyzed at the beginning (1) and at the end (2) of the protocol were: variation of peak pressure (ΔPp=Pp2-Pp1),variation of tidal volume (ΔVT =VT2-VT1), variation of dynamic compliance (ΔCdyn= Cdyn2-Cdyn1).
- The amount of variation of mucus secretion aspirated (ΔSa= Sa2-Sa1) at the end was also measured
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||66 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Increasing Pressure Support During Chest Wall Compression is Useful During Respiratory Therapy?|
|Study Start Date :||May 2008|
|Actual Primary Completion Date :||June 2009|
|Actual Study Completion Date :||May 2010|
Experimental: PSV group.
Chest wall compression plus increase of 10 cmH2O of PSV.
Device: Chest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest.
Active Comparator: chest wall compression group
Chest wall compression
Device: Chest wall compression for ten minutes in chest
- Variation of mucus secretion aspirated. [ Time Frame: Two years ]
- Hemodynamic and pulmonary parameters. [ Time Frame: Two years ]The hemodynamic and pulmonary parameters were collected: Hart rate (HH), respiratory rate (f), mean arterial pressure (MAP) and peripheral arterial saturation of oxygen (SpO2); peak inspiratory pressure (Ppeak),and Tidal volume (VT) measured in the ventilator, dynamic compliance (Cdyn calculated through the formula VT/ Ppeak - PEEP)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01155648
|Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre|
|Porto Alegre, Rio Grande do Sul, Brazil, 90035-903|
|Principal Investigator:||Silvia R Vieira, PhD||Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre|