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Effects of Physical Exercise in Type 2 Diabetics

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ClinicalTrials.gov Identifier: NCT01095068
Recruitment Status : Terminated
First Posted : March 29, 2010
Last Update Posted : October 5, 2017
Sponsor:
Information provided by (Responsible Party):
University Hospital, Strasbourg, France

Brief Summary:
The aim of this study is to evaluate the improvement in skeletal muscle energetic capacity, endothelial dysfunction and glycemic control induced by physical training in 20 sedentary patients with a type 2 diabetes.The protocol consists in a physical training program with 3 sessions of 30 minutes per week during six consecutive weeks. A skeletal muscle biopsy, a cardiac and humeral artery ultrasounds, a glycemic and tensional holters will be performed before and at the end of the physical training program.

Condition or disease Intervention/treatment Phase
Type 2 Diabetes Mellitus Behavioral: Physical exercise Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 15 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Beneficial Effects of Exercise Training on Physical Capacity in Type 2 Diabetics: Improvement in Skeletal Muscle Energetic Capacity, Endothelial Dysfunction and Glycemic Control
Study Start Date : March 2010
Actual Primary Completion Date : August 2014
Actual Study Completion Date : August 2014

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: physical exercise
Physical exercise
Behavioral: Physical exercise




Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • sedentary adult with type 2 diabetes
  • BMI between 25 and 35 kg/m²
  • Hba1c < 10 %

Exclusion Criteria:

  • unstable coronary artery disease
  • advanced peripheral occlusive arterial disease
  • proteinuria > 3 g/d and / or creatinine clearance < 30 ml / mn
  • advanced diabetic neuropathy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01095068


Locations
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France
Médecine Interne et Nutrition, Hôpital Civil, Hôpitaux universitaires de Strasbourg
Strasbourg, France, 67091
Service de Physiologie et d'Explorations Fonctionnelles, Nouvel Hôpital Civil, Hôpitaux universitaires de Strasbourg
Strasbourg, France, 67091
Service de Médecine Interne et Nutrition, Hôpital de Hautepierre, Hôpitaux universitaires de Strasbourg
Strasbourg, France, 67098
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
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Principal Investigator: Alain PRADIGNAC, MD Hôpitaux universitaires de Strasbourg

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Responsible Party: University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT01095068     History of Changes
Other Study ID Numbers: 3661
First Posted: March 29, 2010    Key Record Dates
Last Update Posted: October 5, 2017
Last Verified: September 2017

Additional relevant MeSH terms:
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Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases