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The aim of this study is to evaluate the improvement in skeletal muscle energetic capacity, endothelial dysfunction and glycemic control induced by physical training in 20 sedentary patients with a type 2 diabetes.The protocol consists in a physical training program with 3 sessions of 30 minutes per week during six consecutive weeks. A skeletal muscle biopsy, a cardiac and humeral artery ultrasounds, a glycemic and tensional holters will be performed before and at the end of the physical training program.
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Layout table for eligibility information
Ages Eligible for Study:
40 Years to 70 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
sedentary adult with type 2 diabetes
BMI between 25 and 35 kg/m²
Hba1c < 10 %
unstable coronary artery disease
advanced peripheral occlusive arterial disease
proteinuria > 3 g/d and / or creatinine clearance < 30 ml / mn