Working...
ClinicalTrials.gov
ClinicalTrials.gov Menu

Proteinuria in Pre and Post Transplant

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01094327
Recruitment Status : Recruiting
First Posted : March 26, 2010
Last Update Posted : July 23, 2019
Sponsor:
Information provided by (Responsible Party):
George W. Burke, University of Miami

Brief Summary:
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.

Condition or disease
Proteinuria

Detailed Description:
This study will retrospectively review patient's medical records for protein in the urine, blood creatinine and kidney biopsy results. Also character of the fluid used to flush the kidney before transplant will be analyzed.

Layout table for study information
Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Other
Time Perspective: Retrospective
Official Title: Evaluation of Recipients With and Without Proteinuria, Pre and Post Kidney Transplantation
Study Start Date : February 2008
Estimated Primary Completion Date : December 2020
Estimated Study Completion Date : December 2020

Resource links provided by the National Library of Medicine






Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   up to 25 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Pediatric population up to the age of 25 years old, with biopsy diagnosed of FSGS (focal segmental glomerulosclerosis).
Criteria

Inclusion Criteria:

  • Kidney transplant recipients
  • Pediatric males and females up to the age of 25 years old.

Exclusion Criteria:

  • Transplant recipients other than kidney

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01094327


Contacts
Layout table for location contacts
Contact: George Burke, M.D. 305-355-5111 gburke@med.miami.edu
Contact: Lissett Tueros 305-355-5315 ltueros@med.miami.edu

Locations
Layout table for location information
United States, Florida
University of Miami Miller School of Medicine Transplant Clinic Recruiting
Miami, Florida, United States, 33136
Contact: George Burke, M.D.    305-355-5111    gburke@med.miami.edu   
Principal Investigator: George Burke, M.D.         
Sponsors and Collaborators
University of Miami
Investigators
Layout table for investigator information
Principal Investigator: George Burke, M.D. University of Miami

Layout table for additonal information
Responsible Party: George W. Burke, Professor of Surgery, University of Miami
ClinicalTrials.gov Identifier: NCT01094327     History of Changes
Other Study ID Numbers: 20070206
First Posted: March 26, 2010    Key Record Dates
Last Update Posted: July 23, 2019
Last Verified: July 2019

Keywords provided by George W. Burke, University of Miami:
focal segmental glomerulosclerosis

Additional relevant MeSH terms:
Layout table for MeSH terms
Proteinuria
Urination Disorders
Urologic Diseases
Urological Manifestations
Signs and Symptoms