Study of Effects of L-Arginine in Colitis and Colon Cancer
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|ClinicalTrials.gov Identifier: NCT01091558|
Recruitment Status : Completed
First Posted : March 24, 2010
Last Update Posted : March 31, 2017
The purpose of this study is to look at the importance of L-Arginine in the digestive tract. L-Arginine is an amino acid and is important in making proteins within the cell.
The evaluation of colon tissue, blood, urine, diet, health history, and symptoms will help us learn more about L-Arginine and ulcerative colitis. The investigators believe these studies will provide new insights into the treatment for Inflammatory Bowel Disease (ulcerative colitis) and nutritional needs. The investigators plan to enroll 200 participants in this study over the next two years.
|Condition or disease|
|Ulcerative Colitis Colon Cancer|
|Study Type :||Observational|
|Actual Enrollment :||204 participants|
|Official Title:||Immunomodulary Effects of Arginine Supplementation in Colitis and Colon Cancer|
|Study Start Date :||September 2009|
|Actual Primary Completion Date :||December 2011|
|Actual Study Completion Date :||December 2011|
Healthy volunteer who is having a screening colonoscopy
Patients with confirmed ulcerative colitis who are scheduled for endoscopy for medical reasons.
- L-Arginine (L-Arg) availability in ulcerative colitis (UC) patients and normal control subjects, and correlate with disease activity [ Time Frame: 24 months ]
- L-Arg intake in the diet of UC patients and control subjects [ Time Frame: 24 months ]
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01091558
|United States, Tennessee|
|Nashville, Tennessee, United States, 37232|
|Principal Investigator:||Keith Wilson, MD, AGAF||Vanderbilt University Medical Center|