Solar Disinfection of Drinking Water (SODISWATER)
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|ClinicalTrials.gov Identifier: NCT01082107|
Recruitment Status : Completed
First Posted : March 8, 2010
Last Update Posted : March 8, 2010
SODISWATER is a European Union funded health impact assessment study investigating the effect of sunlight to inactivate microbial pathogens in drinking water. This study was done by observing whether children younger than 5 years old who drink solar disinfected water were healthier than those who did not. Health was measured by how often the children had diarrhoea.
Participants were given plastic bottles to place in the sun, water samples were then collected from these plastic bottles to be analyzed. They were also requested to fill in diarrhea diaries.
TESTABLE RESEARCH HYPOTHESES:
Health Impact Assessment: Children who use solar disinfected water will have:
(a) lower morbidity due to non-bloody diarrhoea and bloody diarrhoea (c) increased growth rates (d) lower mortality (e) increased family productivity (f) decreased care-giver burden (g) increased school attendance
|Condition or disease||Intervention/treatment||Phase|
|Diarrhea Dysentery (Bloody Diarrhea)||Other: Solar disinfection in transparent containers (plastic bottles)||Not Applicable|
The current evidence base for solar disinfection in the prevention of diarrhoeal disease in children rests on three published studies. All share two significant weaknesses: all were carried out in Kenya, in communities which have very high incidences of diarrhoeal disease and water characterised by high levels of both turbidity and microbial contamination. Furthermore, neither of the studies of diarrhoeal disease distinguished between dysentery (associated with significant risk of mortality) and other sorts of diarrhoea, which carry a far lower risk. The present study will extend the evidence base into communities at lower risk and with higher water quality. Furthermore, by using pictorial diaries, dysentery can be analysed as a specific health endpoint. Diarrhoea will be recorded consistent with the World Health organisation definition: three or more loose or watery stools in a 24-hour period and/or stools containing blood or mucus.
AIM OF THE PROJECT IN RELATION TO HEALTH IMPACT ASSESSMENT STUDIES:
The primary aim of the SODISWATER PROJECT is to demonstrate that SODIS is an appropriate intervention against diarrhoeal and waterborne disease among communities in developing countries and those affected by natural or man-made disasters by conducting multi-centred epidemiologically controlled Health Impact Assessments of the SODIS technique across the African Continent under a variety of social, geographical and climactic conditions.
SCIENTIFIC OBJECTIVES OF SODISWATER IN RELATION TO HEALTH IMPACT ASSESSMENT STUDIES:
- Assessment of the change in health reasonably attributed to the provision of solar disinfected drinking water at the point of use in four African countries
- Assessment of the relationship between solar disinfected drinking water and selected health indicators (including morbidity due to non-bloody diarrhoea and dysentery, weight loss, mortality, growth rates, productivity, care-giver burden, and school attendance. Mortality will also be monitored but the sample sizes are of insufficient size to produce detailed information and scaling up, to account for this is not possible due to prohibitive costs).
- Demonstration of the effectiveness of SODIS at household level.
- Assessment of gender specific issues.
- Demonstration of the degree of acceptance/ compliance of SODIS as a disinfection method.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||800 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Solar Disinfection of Drinking Water for Use in Developing Countries or in Emergency Situations|
|Study Start Date :||October 2006|
|Actual Study Completion Date :||August 2009|
|Solar disinfection of drinking water||
Other: Solar disinfection in transparent containers (plastic bottles)
Participants in the study drink solar disinfected (SODIS) water. Solar disinfected water is water (> 3 L) that has been placed in direct sunlight for 6 hours. Participants are expected to drink SODIS treated water for the duration of the study.
- Reduction in dysentery and non-dysentery diarrhoeal disease in children under five years old [ Time Frame: Duration of the study ]The method comprises pictorial or smiley diaries that record diarrhoea consistent with the World Health Organisation definition: three or more loose or watery stools in a 24-hour period and/or stools containing blood or mucus.The smiley diary allows a person to note any diarrhoeal episodes themselves on a recording form on a daily basis. The happy face is marked by the parent or carer when the child passes a normal stool. If a loose or watery stool is passed by the child, one of the sad faces is marked, and if the child passes blood or mucus in his or her stools the special box is marked.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01082107
|Council for Scientific and Industrial Research (CSIR)|
|Pretoria, Gauteng, South Africa, 0001|
|Principal Investigator:||Kevin G McGuigan, PhD||Royal College of Surgeons, Ireland|