Cognitive and Mood Effects of Docosahexaenoic Acid (DHA)-Rich and Eicosapentaenoic Acid (EPA)-Rich Fish Oil in Healthy Young Adults
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01075919 |
Recruitment Status :
Completed
First Posted : February 25, 2010
Last Update Posted : February 25, 2010
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Cognitive Function Mood | Dietary Supplement: n-3 PUFAs Dietary Supplement: Placebo | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 159 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Triple (Participant, Investigator, Outcomes Assessor) |
Primary Purpose: | Basic Science |
Official Title: | Cognitive and Mood Effects of DHA-rich and EPA-rich Fish Oil in Healthy Young Adults |
Study Start Date : | December 2007 |
Actual Primary Completion Date : | December 2008 |
Actual Study Completion Date : | December 2008 |

Arm | Intervention/treatment |
---|---|
Active Comparator: DHA-rich fish oil
1 g DHA-rich fish oil containing 450 mg DHA + 90 mg EPA
|
Dietary Supplement: n-3 PUFAs
1 g DHA-rich fish oil taken daily for 12 weeks |
Active Comparator: EPA-rich fish oil
1 g EPA-rich fish oil containing 300 mg EPA + 200 mg DHA
|
Dietary Supplement: n-3 PUFAs
1 g EPA-rich fish oil taken daily for 12 weeks |
Placebo Comparator: Placebo
1 g Olive oil
|
Dietary Supplement: Placebo
1 g olive oil taken daily for 12 weeks |
- Cognitive performance [ Time Frame: 12 weeks ]Performance is assessed using the COMPASS (Computerised Mental Performance Assessment) system, which presents a battery of standard cognitive tasks assessing aspects of attention, memory and executive function. The Cognitive Demand Battery (30 minutes)will also be administered and assesses cognitive performance under mental fatigue.
- Mood [ Time Frame: 12 weeks ]Mood will be evaluated using Bond-Lader VAS and the Depression, Anxiety and Stress Scales.

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years to 35 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Male/Female
- 18-35 years
- Healthy
- No herbal supplements/prescription medications (excl. contraceptive pill)
- Non smoker
- Native English speaker
Exclusion Criteria:
- Consumes ≥ 1 portion oily fish/week
- takes omega-3 supplement
- Food allergies to treatment ingredients

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01075919
United Kingdom | |
Northumbria University | |
Newcastle upon Tyne, Tyne and Wear, United Kingdom, NE1 8ST |
Principal Investigator: | Philippa A Jackson | Northumbria University |
Responsible Party: | Philippa Jackson, Northumbria University |
ClinicalTrials.gov Identifier: | NCT01075919 |
Other Study ID Numbers: |
16N1 |
First Posted: | February 25, 2010 Key Record Dates |
Last Update Posted: | February 25, 2010 |
Last Verified: | February 2010 |
n-3 PUFAs Cognitive function Healthy young adults Fish oil Mood |