Tear Film Thickness Measured Using a Novel Technique
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01014780|
Recruitment Status : Completed
First Posted : November 17, 2009
Last Update Posted : October 11, 2010
The aim of this investigation is to determine the thickness of the human preocular tear film using a new method based on laser speckle. This will be a preliminary study to generate "normative" tear film thickness data in normal (i.e., non dry eye) and dry eye subjects in a clinic-based population. In addition, we will examine the short term (i.e., one week) repeatability of the method in a single setting.
The patients classified as having dry eye will also have their tear film thickness measured after instillation of an artificial tear. This will potentially reveal valuable data in retention of effect measured non-invasively as in prior studies that employed a fluorescein tracer.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||40 participants|
|Official Title:||Tear Film Thickness Measured Using a Novel Technique|
|Study Start Date :||November 2009|
|Actual Primary Completion Date :||April 2010|
|Actual Study Completion Date :||October 2010|
Normal (non-dry) dry eye subjects
These are healthy individuals, age 18 and above, who do not exhibit dry eyes by signs and symptoms
Dry eye subjects
These are subjects, age 18 years and above, who do exhibit signs and symptoms of dry eye.
- Tear film thickness in normal eyes [ Time Frame: 1-3 months ]
- Tear thickness change following viscous drop instillation [ Time Frame: 1-3 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01014780
|United States, California|
|Southern California College of Optometry|
|Fullerton, California, United States, 92831`|
|Study Director:||Jerry Paugh, OD. PhD||Southern California College of Optometry|