Antibiotic Therapy of Acute Uncomplicated Colonic Diverticulitis
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|ClinicalTrials.gov Identifier: NCT01008488|
Recruitment Status : Completed
First Posted : November 5, 2009
Last Update Posted : December 23, 2011
The purpose of this study is to evaluate if antibiotic therapy is necessary for treatment of uncomplicated colonic diverticulitis.
The hypothesis is that Patients with acute uncomplicated colonic diverticulitis will recover the condition without antibiotic therapy and the lack of antibiotic therapy will not lead to complications.
The patients will be randomized to conservative treatment with and without antibiotic therapy.
|Condition or disease||Intervention/treatment||Phase|
|Colonic Diverticulitis||Drug: Antibiotic||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||600 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Is Antibiotic Therapy Mandatory for Treatment of Uncomplicated Acute Colonic Diverticulitis: a Randomized Clinical Trial|
|Study Start Date :||November 2002|
|Actual Primary Completion Date :||May 2010|
|Actual Study Completion Date :||December 2010|
|Active Comparator: Antibiotic||
Antibiotic according to local treatment routine against bowel pathogenesis
|No Intervention: No antibiotic|
- discharge without complications +/- antibiotic therapy [ Time Frame: Within 30 days after discharge ]
- to evaluate length of hospital stay, cost and late complications [ Time Frame: one year after admission ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01008488
|The Central Hospital|
|Västerås, Västmanland, Sweden|
|Principal Investigator:||Kenneth Smedh||Center of Clinical Research, Västerås|