Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury
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The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver.
Condition or disease
Drug Induced Liver Injury
Our hypothesis is that there are liver-specific particles, called mRNA, that are identifiable in a person's blood sample during liver injury caused by some drugs. The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver, perhaps early in the process before significant injury or illness have occurred.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 80 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients will be identified in emergency rooms or inpatients at the University of North Carolina Memorial Hospital.
ALT > 200 IU/L at presentation to UNC Hospitals
Drug induced liver injury considered likely by admitting medical staff