Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols
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|ClinicalTrials.gov Identifier: NCT00987155|
Recruitment Status : Completed
First Posted : September 30, 2009
Last Update Posted : January 18, 2017
- Measurements of peak oxygen uptake (VO2peak) during passive leg cycling (PLC) combined with arm crank ergometry (ACE), leg vascular occlusion (100mmHg above systolic BP) combined with ACE, and FES isometric contractions combined with ACE in spinal cord injured (SCI). All the above mentioned parameters will be compared to Functional Electrical Stimulated (FES) lower extremity cycling combined with ACE (FEShybrid). The hypothesis is that VO2peak is significantly higher during FES hybrid cycling when compared to peak and submaximal PLC, leg vascular occlusion and ACE. But the values for VO2peak during FES isometric contractions combined with ACE is not significantly different from FES hybrid cycling.
- Comparison of sub-maximal and peak VO2 values during arm crank (ACE) and wheelchair ergometry (WCE) in persons with spinal cord injury. The hypothesis is that wheelchair propulsion due to higher energy expenditure show higher work output and VO2peak than ACE.
- Does 6 weeks of maximal strength training improve SCI subjects performance during WCE? WCE after 6 weeks maximal strength training is less strenuous owing to better work economy/ efficiency.
- Effect from aerobic high intensity hybrid training on stroke volume (SV) and VO2peak in spinal cord injured men.
8 weeks of high intensity 4 times 4 interval training at 85-90% of peak heart rate during hybrid cycling. Hypothesis; VO2peak and SV will be significantly increased from training.
|Condition or disease||Intervention/treatment||Phase|
|Cardiovascular Disease||Device: Ergometry||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||12 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols|
|Study Start Date :||January 2007|
|Actual Primary Completion Date :||February 2012|
|Actual Study Completion Date :||May 2012|
Experimental: high intensity interval training
8 weeks of high intensity 4 times 4 interval training at 85-90% of peak heart rate during hybrid cycling
MetamaxII Cortex ergospirometry system (Cortex Biophysik GmbH, Germany). Arm cycling ergometer (Ergomed 840L, Siemens, GermanyMonark, Sweden), Electrically braked wheelchair ergometer (VP 100, Handisoft France)
- Maximal oxygen uptake [ Time Frame: 2 years ]
- Blood lactate [ Time Frame: 2 years ]
- Blood Pressure [ Time Frame: 2 years ]
- Perceived Exertion [ Time Frame: 2 years ]
- Generated power (W) [ Time Frame: 2 years ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00987155
|St Olav University Hospital|
|Principal Investigator:||Gunnar Leivseth, Professor MD||NTNU|
|Study Director:||Gisle Meyer||St. Olavs Hospital|
|Study Director:||Lars Jacob Stovner, Professor||NTNU|
|Principal Investigator:||Jan Hoff, Professor||NTNU|
|Principal Investigator:||Berit Brurok, MSc||St. Olavs Hospital|