Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study (FATS)
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|ClinicalTrials.gov Identifier: NCT00976014|
Recruitment Status : Unknown
Verified September 2009 by University of Washington.
Recruitment status was: Enrolling by invitation
First Posted : September 14, 2009
Last Update Posted : September 22, 2009
This observational study looks at Carotid Stenosis in two groups of subjects using a non-invasive procedure, B-mode ultrasound.
One group of subjects has had long-term intensive lipid altering therapy (lowering LDL-C plus raising HDL-C). The second group of patients has been on conventional "standard of care" treatment for carotid stenosis.
The study will look at the Carotid Intima-media Thickness (CMIT) in both groups.
Hypothesis: CIMT will differ between the two groups, such that the CIMT will be less in the subjects on intensive lipid altering therapy.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||55 participants|
|Observational Model:||Case Control|
|Official Title:||Effects of Long-term Therapy With LDL-lowering Plus HDL Raising on Carotid Intima-media Thickness (CIMT) - Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study|
|Study Start Date :||September 2006|
|Estimated Primary Completion Date :||September 2011|
|Estimated Study Completion Date :||September 2011|
Intensive Lipid-lowering therapy
Subjects on intensive long-term lipid lowering therapy (lowering LDL-C plus raising of HDL-C).
Subjects with Atherosclerosis who have been on conventional "standard of care" treatment.
- Carotid Intima-media Thickness [ Time Frame: Up to 3 years ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00976014
|United States, Washington|
|University of Washington|
|Seattle, Washington, United States, 98105|
|Principal Investigator:||Xue-Qiao Zhao||University of Washington|