Intra-articular Glucocorticoid Treatment of the Elbow
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|ClinicalTrials.gov Identifier: NCT00972530|
Recruitment Status : Completed
First Posted : September 7, 2009
Results First Posted : November 11, 2009
Last Update Posted : March 14, 2019
BACKGROUND: Intra-articular glucocorticoid injections are frequently used to relieve symptoms of arthritis. Postinjection rest has been shown to improve the outcome of knee joint injections, but not for wrist injections. Consequently, different joints respond differently on postinjection regimens.
OBJECTIVES: To investigate whether better treatment results might be achieved of post-injection rest following intra-articular glucocorticoid treatment for elbow synovitis.
METHODS: 90 patients with rheumatoid arthritis (RA) and elbow synovitis were treated with 20 mg intra-articular triamcinolone hexacetonide and randomised to either a 48 hour immobilisation in a triangular sling (n=46) or normal activity without restrictions (n=44). Primary endpoint was relapse of synovitis. In addition, pain, function according to a self assessment questionnaire (PREE) and range of movement were followed for six months.
|Condition or disease||Intervention/treatment||Phase|
|Rheumatoid Arthritis||Behavioral: immobilisation in a triangular sling||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||90 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||The Importance of Immobilisation After Intra-articular Glucocorticoid Treatment for Elbow Synovitis - a Randomised and Controlled Study|
|Study Start Date :||January 2006|
|Actual Primary Completion Date :||December 2008|
|Actual Study Completion Date :||December 2008|
No Intervention: Activity
Normal activity without restrictions
Active Comparator: immobilisation
48 hours postinjection rest
Behavioral: immobilisation in a triangular sling
Intervention group: Immobilisation 48 hours in a triangular sling (mitella)
Control group: normal activity without restrictions
- Relapse of Arthritis [ Time Frame: Regular visits at one week, 3 months and 6 months. ]The patients were followed for six months and if signs and symptoms recurred in between the patients were told to contact the rheumatology department. In such cases the elbow was re-examined and if a relapse could be confirmed the duration of effect was recorded and if needed the patient was offered another injection.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00972530
|Principal Investigator:||Tomas Weitoft, MD PhD||Department of Research and Development County Council of Gävleborg/Uppsala University|