A Pilot Study of Migraine and Appetite Behaviour in Children
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|ClinicalTrials.gov Identifier: NCT00930852|
Recruitment Status : Completed
First Posted : July 2, 2009
Last Update Posted : February 22, 2012
|Condition or disease|
|Migraine Disorders Obesity|
Migraine is a chronic neurological disorder characterized by recurrent episodes of headache and associated symptoms. The condition affects approximately 11% of the child population and it can impose considerable burdens on the sufferer either due to the headache itself, or associated co-morbidities such as psychological stress, obesity, sleep problems, etc. Increasing attention is focussing on the shared genetic, environmental and neurobiological mechanisms of migraine co-morbidities to gain further insights into improving outcomes.
We are interested in studying eating behaviours in children with migraine since there is evidence that altered patterns of eating behaviour (and underlying changes in appetite) are seen in migraineurs although not studied systematically. Altered appetite and eating behaviours may be a mechanism for the emerging association between obesity (or degree of adiposity) and migraine severity, detected in both adult and paediatric studies to varying extents. Studying the putative association between migraine, degree of adiposity and patterns of eating behaviour in children may help to tease out causal mechanisms, since both migraine and obesity often evolve over the course of childhood.
|Study Type :||Observational|
|Actual Enrollment :||60 participants|
|Official Title:||Migraine, Appetite Behaviour and Obesity: is There a Link?. A Pilot Study of Migraine and Appetite Behaviour in Children.|
|Study Start Date :||July 2009|
|Actual Primary Completion Date :||August 2010|
|Actual Study Completion Date :||August 2010|
- Pearson's correlation between PedMIDAS score (measure of migraine severity) and eating behaviour subscale score on the Child Eating Behaviour Questionnaire or Dutch Eating Behaviour Questionnaire.
- Regression coefficient of PedMIDAS score or categories of headache frequency on eating behaviour subscale scores, with covariates of Achenbach Child Behavior Checklist score, current BMI, age, sex, length of history of migraine.
- Descriptive analysis of type and severity of typical food cravings and dietary habits using the Food Craving Inventory score and a food intake questionnaire.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00930852
|Alder Hey Children's Hospital|
|Liverpool, Merseyside, United Kingdom, L12 2AP|
|Principal Investigator:||Ram Kumar, MRCP||Alder Hey Children's NHS Foundation Trust|