COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Survey and Cognitive Behavior Therapy for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00920777
Recruitment Status : Completed
First Posted : June 15, 2009
Last Update Posted : June 9, 2020
St. Olavs Hospital
Information provided by (Responsible Party):
Norwegian University of Science and Technology

Brief Summary:
The purpose of this study is to analyze income variables in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, and to analyze the effect of short vs. long Cognitive Behaviour Therapy.

Condition or disease Intervention/treatment Phase
Chronic Fatigue Syndrome Myalgic Encephalomyelitis Fatigue Pain Behavioral: CBT Behavioral: Control group Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 234 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: A RCT Study on the Effect of Short and Long Cognitive Behaviour Therapy (CBT) in CFS/ME Patients
Study Start Date : May 2009
Actual Primary Completion Date : July 2014
Actual Study Completion Date : May 2015

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: 8 weeks CBT Behavioral: CBT
Individual Cognitive Behavior Therapy during 8 weeks

Active Comparator: Control group Behavioral: Control group
Waiting 16 weeks and receiving 8 weeks individual CBT after waiting period.

Experimental: 16 weeks CBT Behavioral: CBT
Individual Cognitive Behavior Therapy during 16 weeks
Other Name: Grades excercise therapy

Primary Outcome Measures :
  1. Mental and physical function [ Time Frame: 1 year ]
    Mental and physical function, measured by "SF 36". Success criteria are measured by >10 point improvement of mental and/ or physical function.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years to 62 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients referred to St.Olav Hospital, Trondheim
  • fulfil the FUKUDA criteria for CFS/ME.

Exclusion Criteria:

  • Pregnant patients

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00920777

Layout table for location information
St.Olavs Hospital
Trondheim, Norway, 7006
Sponsors and Collaborators
Norwegian University of Science and Technology
St. Olavs Hospital
Layout table for investigator information
Principal Investigator: Egil Fors, prof MD St. Olavs Hospital
Publications of Results:
Layout table for additonal information
Responsible Party: Norwegian University of Science and Technology Identifier: NCT00920777    
Other Study ID Numbers: 21592
21592 ( Other Identifier: NSD )
4.2008.2586 ( Other Identifier: REK )
First Posted: June 15, 2009    Key Record Dates
Last Update Posted: June 9, 2020
Last Verified: June 2020
Keywords provided by Norwegian University of Science and Technology:
Fukuda criteria
Mental functioning
Physical functioning
Additional relevant MeSH terms:
Layout table for MeSH terms
Fatigue Syndrome, Chronic
Pathologic Processes
Virus Diseases
Muscular Diseases
Musculoskeletal Diseases
Central Nervous System Diseases
Nervous System Diseases
Neuromuscular Diseases
Central Nervous System Infections
Musculoskeletal Pain
Neurologic Manifestations