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Using Duke Activity Status Index (DASI) to Select Optimal Cardiac Stress Tests (DASI-08-713)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00907855
Recruitment Status : Completed
First Posted : May 25, 2009
Last Update Posted : November 30, 2011
Astellas Pharma Inc
Information provided by (Responsible Party):
Lawrence Phillips, MD, NYU Langone Health

Brief Summary:

Cardiac stress testing with functional nuclear imaging is an invaluable technique in the diagnostic and prognostic evaluation of patients with known or suspected ischemic heart disease. Selection of the appropriate type of nuclear stress test: exercise stress Myocardial Perfusion Imaging (MPI) versus pharmacologic stress MPI is crucial for not only diagnostic accuracy and prognostic evaluation, but also for sound clinical decisions and resource utilization.

The Duke Activity Status Index (DASI) is a 12-item questionnaire that utilized self-reported physical work capacity to estimate peak metabolic equivalents (METs) and has been shown to be a valid measurement of functional capacity. The investigators hypothesized that the DASI may be the screening tool that evaluates functional capacity and guides selection of the optimal stress MPI study.

Condition or disease
Ischemic Heart Disease

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Study Type : Observational
Actual Enrollment : 200 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Clinical Role of the Duke Activity Status Index in the Selection of the Optimal Type of Stress Myocardial Perfusion Imaging Study in Patients With Known or Suspected Ischemic Heart Disease
Study Start Date : April 2009

Resource links provided by the National Library of Medicine

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients referred by their primary physician to the Nuclear Lab at NYU School of Medicine for stress myocardial perfusion imaging testing.

Inclusion Criteria:

  • Age > 18

Exclusion Criteria:

  • None

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00907855

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United States, New York
Nuclear Cardiology/Stress Lab, NYU Cardiology Division
New York, New York, United States, 10016
Sponsors and Collaborators
NYU Langone Health
Astellas Pharma Inc
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Principal Investigator: Jennifer H. Mieres, MD Division of Cardiology, New York University School of Medicine
Study Director: Lawrence Phillips, MD Division of Cardiology, New York University School of Medicine
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Responsible Party: Lawrence Phillips, MD, Director, Nuclear Cardiology, NYU Langone Health Identifier: NCT00907855    
Other Study ID Numbers: NYU DASI 08-713
First Posted: May 25, 2009    Key Record Dates
Last Update Posted: November 30, 2011
Last Verified: November 2011
Keywords provided by Lawrence Phillips, MD, NYU Langone Health:
Ischemic Heart Disease
Duke Activity Status Index
Stress Myocardial Perfusion Imaging
Additional relevant MeSH terms:
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Heart Diseases
Myocardial Ischemia
Coronary Artery Disease
Pathologic Processes
Cardiovascular Diseases
Vascular Diseases
Coronary Disease
Arterial Occlusive Diseases