A Continuation Clinical Trial of Oral Vorinostat (MK-0683) in Advanced Cancers (MK-0683-007)
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|ClinicalTrials.gov Identifier: NCT00907738|
Recruitment Status : Completed
First Posted : May 25, 2009
Results First Posted : July 14, 2011
Last Update Posted : May 21, 2015
|Condition or disease||Intervention/treatment||Phase|
|Advanced Cancer||Drug: vorinostat||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||27 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Continuation Clinical Trial of Oral Vorinostat (MK-0683) in Advanced Cancers|
|Study Start Date :||August 2005|
|Actual Primary Completion Date :||June 2010|
|Actual Study Completion Date :||June 2010|
All patients will receive vorinostat at the same dose and schedule as they received in the base protocol until disease progression or unacceptable toxicity.
Other Name: MK-0683
- Percent of Participants With a Serious Drug-related Adverse Event (AE) [ Time Frame: From the first dose of study drug until the patient experiences disease progression, withdraws consent, or develops unacceptable toxicity (from Day 1 up to 4 years and 9 months) ]
A serious adverse event (SAE) was any AE occurring at any dose that resulted in death, was life-threatening, resulted in a persistent or significant disability/incapacity, resulted in or prolonged an existing inpatient hospitalization, was a congenital anomaly/birth defect, was a cancer, or was an overdose.
A drug-related SAE was one that was thought to be possibly, probably, or definitely related to the study drug.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00907738
|Study Director:||Medical Monitor||Merck Sharp & Dohme Corp.|