Brachial Artery Peak Velocity Variation to Predict Fluid Responsiveness
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|ClinicalTrials.gov Identifier: NCT00890071|
Recruitment Status : Completed
First Posted : April 29, 2009
Last Update Posted : April 29, 2009
|Condition or disease||Intervention/treatment|
|Hypotension Shock||Other: Fluid administration|
Predicting the hemodynamic response to fluid administration (or fluid responsiveness) in critical ill patients is still a matter of concern, since fluid overload could worse the clinical situation of these patients. Parameters of fluid responsiveness usually require an invasive monitoring (like arterial pulse pressure variation).
We hypothesize that noninvasive evaluation of respiratory variation of peak velocity in brachial artery using Doppler ultrasound could provide a feasible estimation on fluid responsiveness in mechanically ventilated patients with acute circulatory failure.
|Study Type :||Observational|
|Actual Enrollment :||38 participants|
|Official Title:||Brachial Artery Peak Velocity Variation to Predict Fluid Responsiveness in Mechanically Ventilated Patients|
|Study Start Date :||December 2008|
|Actual Primary Completion Date :||March 2009|
|Actual Study Completion Date :||April 2009|
Acute circulatory failure
Patients for whom the decision to give fluids was taken because the presence of one or more clinical signs of acute circulatory failure.
Other: Fluid administration
500 ml of synthetic colloid (Voluven®, hydroxyethylstarch 6%; Fresenius, Bad Homburg, Germany) infused over 30 minutes
- Predictive value of respiratory variation in brachial artery peak velocity before volume expansion assessed by ROC curve. We defined responser as patients that increased stroke volume index equal or more than 15% after fluid administration. [ Time Frame: immediately after volume expansion ]
- Evaluate the predictive value of pulse pressure variation for predicting hemodynamic response to fluid administration, comparing with the predictive value of respiratory variation of brachial artery peak velocity. [ Time Frame: immediately after fluid administration ]
- Evaluate the predictive value of stroke volume variation for predicting hemodynamic response to fluid administration, comparing with the predictive value of respiratory variation of brachial artery peak velocity. [ Time Frame: immediately after volume expansion ]
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00890071
|Hospital del SAS de Jerez|
|Jerez de la Frontera, Cádiz, Spain, 11407|
|Principal Investigator:||M. Ignacio Monge García||Hospital del SAS de Jerez|