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Central Venous Catheter Lock Solution (CVCLS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00862966
Recruitment Status : Unknown
Verified March 2009 by University Medical Center, Tuzla.
Recruitment status was:  Not yet recruiting
First Posted : March 17, 2009
Last Update Posted : March 17, 2009
Information provided by:
University Medical Center, Tuzla

Brief Summary:
The purpose of this study is to determine whether the application of 47% citrate lock solution decreases the incidence of infection and thrombosis of central venous catheter in hemodialysis population.

Condition or disease Intervention/treatment Phase
Bacteremia Other: citrate Other: heparin Not Applicable

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 40 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Randomized Control Trial on Citrate as the Central Venous Catheter Lock Solution
Study Start Date : April 2009
Estimated Primary Completion Date : April 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Blood Thinners

Arm Intervention/treatment
Experimental: citrate Other: citrate
comparison of different catheter lock solutions

Active Comparator: heparin Other: heparin
comparison of different lock solutions

Primary Outcome Measures :
  1. lower incidence of infection [ Time Frame: 1 year ]

Secondary Outcome Measures :
  1. lower incidence of thrombosis [ Time Frame: 1 year ]

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Clinical diagnosis of end stage renal disease

Exclusion Criteria:

  • Patients refusing randomization

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00862966

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Contact: Goran Imamovic, MD, PhD +387 61 194 131

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Bosnia and Herzegovina
Department of Dialysis
Tuzla, TK, Bosnia and Herzegovina, 75000
Contact: Goran Imamovic, MD,PhD    +387 61 194 131   
Principal Investigator: Goran Imamovic, MD, PhD         
Sponsors and Collaborators
University Medical Center, Tuzla
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Responsible Party: UNIVERSITY MEDICAL CENTER, Department of Dialysis Identifier: NCT00862966    
Other Study ID Numbers: UMC-02-139
First Posted: March 17, 2009    Key Record Dates
Last Update Posted: March 17, 2009
Last Verified: March 2009
Additional relevant MeSH terms:
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Bacterial Infections
Systemic Inflammatory Response Syndrome
Pathologic Processes
Molecular Mechanisms of Pharmacological Action
Fibrinolytic Agents
Fibrin Modulating Agents