Muscle Strength and Exercise Capacity in Sarcoidosis Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00854672|
Recruitment Status : Completed
First Posted : March 3, 2009
Last Update Posted : April 6, 2012
|Condition or disease|
The aim of this study is to examine exercise capacity, muscle strength and fatigue in sarcoidosis. In this longitudinal study the changes in prevalence of exercise intolerance, reduced muscle strength and fatigue will be established in a two-year follow-up. Also the relation between these physical impairments in time and other clinical parameters, such as QOL, will be established.
Study design: sarcoidosis patients referred to the ild care team of outpatient clinic of the department of Respiratory Medicine of the MUMC and also participated in the baseline study between November 2008 and September 2009 will be included in this longitudinal study. A six-minute walk test and peripheral muscle strength measurements (included in the regular clinical work-up of sarcoidosis patients) will be performed under supervision of a physical therapist at the department of physical therapy of the MUMC. Moreover, the patients will be asked to complete the WHOQOL-bref questionnaire and the Fatigue Assessment Scale. A maximum of 124 patients will be included.
|Study Type :||Observational|
|Actual Enrollment :||124 participants|
|Official Title:||Exercise Capacity, Muscle Strength and Fatigue in Sarcoidosis: a Two-year Follow-up Study|
|Study Start Date :||January 2009|
|Actual Primary Completion Date :||August 2009|
|Actual Study Completion Date :||September 2011|
Sarcoidosis patients referred to the ild care team of the outpatient clinic of the department of Respiratory Medicine of the MUMC and also participated in the baseline study between November 2008 and September 2009 will be included in this study
- Exercise capacity, muscle strength and fatigue in sarcoidosis: a two-year follow-up study [ Time Frame: 30 months ]6MWD and muscle strength measurements of arm (isometric strength of the elbow flexors) and leg (isokinetic peak torques of the hamstrings and quadriceps) muscles. Questionnaires: WHOQOL-bref and Fatigue Assessment Scale (FAS).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00854672
|Maastricht University Medical Center|
|Principal Investigator:||Rik Marcellis, MSc||Maastricht University Medical Center|
|Study Chair:||Marjolein Drent, MD, PhD||Maastricht University Medical Center and University Maastricht|
|Study Director:||Ton Lenssen, MSc, PhD||Maastricht UMC and University of Maastricht|