Canadian Study of Prediction of Risk and Evolution to Dialysis, Death and Interim Cardiovascular Events Over Time (CanPREDDICT)
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|ClinicalTrials.gov Identifier: NCT00826319|
Recruitment Status : Unknown
Verified November 2013 by University of British Columbia.
Recruitment status was: Active, not recruiting
First Posted : January 22, 2009
Last Update Posted : November 28, 2013
|Condition or disease|
|Chronic Kidney Disease|
|Study Type :||Observational|
|Actual Enrollment :||2602 participants|
|Official Title:||CanPREDDICT: Canadian Study of Prediction of Risk and Evolution to Dialysis, Death and Interim Cardiovascular Events Over Time|
|Study Start Date :||June 2008|
|Estimated Primary Completion Date :||December 2014|
|Estimated Study Completion Date :||December 2014|
Bioimpedance sub-study cohort
Funded by a grant from Kidney Foundation of Canada, Dr. Catherine Clase initiated a bioimpedance sub-study across 7 centres and recruited n=416 within the CANPREDDICT population. The study uses bioimpedance measurements to assess volume status to determine the multivariable relationship between baseline volume overload and subsequent cardiovascular events. Subjects are followed at 6 months intervals for 2 years.
Ethnic enrichment cohort
Additional recruitment initiated and funded by the Principal Investigator, Adeera Levin for enriching the ethnic representation within the Canadian cohort on South Asian and Oriental Asian was completed from Sept 2012 to June 2013, n=53.
Original CanPreddict cohort
The original CanPreddict cohort was recruited from Jun 2008 - Oct 2009 has 2544 CKD patients across Canada.
- Renal Replacement Therapy [ Time Frame: 6 monthly for 3 years, annually up to 5 years ]Renal Replacement Therapy is defined as dialysis start or transplantation.
- Cardiovascular events [ Time Frame: 6 monthly for 3 years, annually up to 5 years ]Cardiovascular events are defined as myocardial infarction, ischemic and hemorrhagic stroke, coronary revascularization, congestive heart failure, peripheral bypass and gangrenes, adjudicated by a nephrologist, cardiologist and neurologist.
- Death [ Time Frame: 6 monthly for 3 years, annually up to 5 years ]Deaths are reported with source documentation and adjudicated for ischemic or congestive cardiovascular death, other cardiovascular death, non-cardiovascular death and unknown cause of death.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00826319
|Principal Investigator:||Adeera Levin||University of British Columbia|