Acute Kidney Injury After Cardiac Surgery Based on KDIGO Criteria
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ClinicalTrials.gov Identifier: NCT00777465 |
Recruitment Status :
Completed
First Posted : October 22, 2008
Last Update Posted : May 21, 2014
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Condition or disease |
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Acute Kidney Injury |
Study Type : | Observational |
Actual Enrollment : | 2804 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | Prognostic Value of Acute Kidney Injury After Cardiac Surgery According to Kidney Disease: Improving Global Outcomes Definition and Staging (KDIGO) Criteria |
Study Start Date : | January 2003 |
Actual Primary Completion Date : | June 2013 |
Actual Study Completion Date : | June 2013 |

Group/Cohort |
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KDIGO 0
Patients with no acute kidney injury after cardiac surgery
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KDIGO 1
Patients with acute kidney injury KDIGO stage 1 after cardiac surgery (Increase in SCr by ≥ 0.3 mg/dL (≥ 26.5 lmol/L) or 1.5 to 1.9 times baseline)
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KDIGO 2
Patients with acute kidney injury KDIGO stage 2 after cardiac surgery (2.0 to 2.9 times baseline SCr)
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KDIGO 3
Patients with acute kidney injury KDIGO stage 3 after cardiac surgery (3.0 times baseline or more; or increase in SCr to ≥ 4.0 mg/dL; or initiation of renal replacement therapy)
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- Acute Kidney Injury after cardiac surgery as a independent predictor of 30-day mortality [ Time Frame: 30 days ]To test the hypothesis that the acute kidney injury based on KDIGO criteria after cardiac surgery is a independent predictor of 30-day mortality

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Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
patients undergoing isolated coronary artery bypass grafting or cardiac valve surgery.
Exclusion Criteria:
patients with incomplete data and patients with end-stage kidney disease.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00777465
Brazil | |
Hospital de Base | |
São José do Rio Preto, São Paulo, Brazil, 15090-000 |
Study Director: | Lilia N Maia, PhD | São José do Rio Preto Medical School |
Responsible Party: | Mauricio de Nassau Machado, Cardiologist in-chief - Coronary Care Unit, Hospital de Base |
ClinicalTrials.gov Identifier: | NCT00777465 |
Other Study ID Numbers: |
CAAE-3436.0.000.140-08 |
First Posted: | October 22, 2008 Key Record Dates |
Last Update Posted: | May 21, 2014 |
Last Verified: | May 2014 |
Acute kidney injury Kidney failure Risk factors Clinical outcomes |
Cardiac valve surgery Coronary artery bypass grafting Morbidity Mortality |
Acute Kidney Injury Wounds and Injuries Renal Insufficiency Kidney Diseases Urologic Diseases |