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The Effect of Dates on Plasma Lipids, Oxidative Stress and the Atherogenicity of Serum in Healthy Adults

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00750789
Recruitment Status : Unknown
Verified September 2008 by HaEmek Medical Center, Israel.
Recruitment status was:  Not yet recruiting
First Posted : September 11, 2008
Last Update Posted : September 11, 2008
Information provided by:
HaEmek Medical Center, Israel

Brief Summary:
It has been proven in in-vitro studies that dates decrease the oxidative stress in serum. There have been no in-vivo studies to this date. The current study aims to test whether dates consumption by healthy adults decreases serum oxidative stress and improves serum PON1 activity and serum lipid profile.

Condition or disease Intervention/treatment Phase
Atherosclerosis Dietary Supplement: dates Phase 4

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 10 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Study Start Date : September 2008
Estimated Primary Completion Date : November 2008

Intervention Details:
  • Dietary Supplement: dates
    5 maedjool dates or 7 emery dates per day for 2 weeks each with a washout period of 2 weeks between

Primary Outcome Measures :
  1. serum oxidative stress [ Time Frame: 30 days ]

Secondary Outcome Measures :
  1. serum lipid profile [ Time Frame: 30 days ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Healthy volunteers

Exclusion Criteria:

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00750789

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Contact: Wasseem Rock, MD 04-6495135

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Emek Medical Center
Afula, Israel
Contact: Wasseem Rock, MD    04-6495135      
Sponsors and Collaborators
HaEmek Medical Center, Israel
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Principal Investigator: Wasseem Rock Emek Medical Center
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Responsible Party: Wasseem Rock, emek medical center Identifier: NCT00750789    
Other Study ID Numbers: 0061-08-EMC
First Posted: September 11, 2008    Key Record Dates
Last Update Posted: September 11, 2008
Last Verified: September 2008
Additional relevant MeSH terms:
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Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases