Transfer From Methadone to Buprenorphine Maintenance Treatment Using Buprenorphine Patches
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ClinicalTrials.gov Identifier: NCT00750217
Recruitment Status : Unknown
Verified August 2008 by Psychiatric University Hospital, Zurich. Recruitment status was: Recruiting
Buprenorphine is an important alternative to methadone in the maintenance treatment of heroin addiction. Transfer from methadone to buprenorphine requires a reduction of daily methadone dosage below 30 mg to avoid withdrawal after the first buprenorphine intake. The study hypothesis states that the transfer from a daily methadone dosage between 60 mg and 100 mg to buprenorphine can be carried out without withdrawal using buprenorphine patches (35 micro grams per hour) within 12 to 48 hours after last methadone intake.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 60 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age between 18 and 60 years
Methadone maintenance treatment for at least 3 months preceding the study
Daily methadone dosage between 60mg amd 100mg
Sufficient knowledge of German language
Ability to give informed consent
Daily methadone dosage below 60mg amd over 100mg
Prescribed use of benzodiazepines over 30 mg equivalent to diazepam