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Evaluation of Thoracic Tumors With 18F-FMT and 18F-FDG PET-CT A Clinicopathological Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00698373
Recruitment Status : Completed
First Posted : June 17, 2008
Last Update Posted : June 17, 2008
Information provided by:
Gunma University

Brief Summary:
L-[3-18F]-α-methyltyrosine (18F-FMT) is an amino-acid tracer for positron emission tomography (PET). The aim of this study was to determine whether PET-CT with 18F-FMT provides additional information for the preoperative diagnostic workup as compared with 18F-FDG PET. Tumor uptake of 18F-FMT was compared with several immunohistochemical markers including L-type amino acid transporter 1 (LAT1).

Condition or disease
Non-Small Cell Lung Cancer

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Study Type : Observational
Time Perspective: Prospective
Official Title: Evaluation of Thoracic Tumors With 18F-FMT and 8F-FDG PET-CT: A Clinicopathological Study

Resource links provided by the National Library of Medicine

PET study

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with indeterminate pulmonary nodule suspicious of lung cancer were eligible for this prospective study.

Inclusion Criteria:

  • Patients with indeterminate pulmonary nodule suspicious of lung cancer

Exclusion Criteria:

  • Patients with other malignancies and those who had received cancer treatment within the past 5 years were excluded.
Layout table for additonal information Identifier: NCT00698373    
Other Study ID Numbers: Molecular FMT imaging
First Posted: June 17, 2008    Key Record Dates
Last Update Posted: June 17, 2008
Last Verified: June 2008
Keywords provided by Gunma University:
Positron emission tomography,
Lung cancer,
Additional relevant MeSH terms:
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Thoracic Neoplasms
Neoplasms by Site