Eustachian Tube Testing in a Pressure Chamber -- Validation Study
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ClinicalTrials.gov Identifier: NCT00694486
Recruitment Status :
First Posted : June 10, 2008
Last Update Posted : February 28, 2019
University of Pittsburgh
National Institute on Deafness and Other Communication Disorders (NIDCD)
This study will compare Eustachian tube function (ETF) testing in adults with intact tympanic membranes (TM) using a pressure chamber to that obtained using standard methods requiring a non-intact TM.
Condition or disease
The investigators propose to introduce new test methods and protocols to our laboratory for better clinical characterization of Eustachian tube function in ears with intact TM's. These test will be done in a pressure-chamber and will use previously published and newly developed methods. Participation will require a minimum of 5 visits to the ENT Research Center, 1 for myringotomy (putting a small hole in the eardrum) and 4 for ETF testing. Hearing testing will be done at entry and exit; otoscopy (looking at the ears) and tympanometry (a test done with an earplug and varying pressures in the ear canal) are done at every visit.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
>18 years old
Normal middle-ear status
Chronic illness including asthma, pulmonary, or cardiac problems
>10 dB hearing loss in any of the speech frequencies
Past history of sensitivity or allergic reaction to lidocaine or related compounds