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Genetics of Symptomatology and Treatment Response in Psychotic Major Depression

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ClinicalTrials.gov Identifier: NCT00691535
Recruitment Status : Completed
First Posted : June 5, 2008
Last Update Posted : June 19, 2019
Sponsor:
Information provided by (Responsible Party):
Alan Schatzberg, Stanford University

Brief Summary:
We hope to learn more about the biology of psychiatric illness with the hope of improving the diagnosis and treatment of such psychiatric conditions as major depression.

Condition or disease
Psychotic Disorders Depressive Disorder Depressive Disorder, Major

Detailed Description:
From the blood sample you donate, the researchers will obtain DNA. This DNA will be used to search for DNA markers related to the underlying biology of psychiatric illness and how this might explain the symptoms of these disorders. Research using DNA is an important way to try to understand human disease and/or the role genes play in disease. In effect, part of your blood sample will be used to attempt to understand how genetic factors contribute to the symptoms of such psychiatric conditions as major depression.

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Study Type : Observational
Enrollment : 500 participants
Time Perspective: Other
Official Title: Association of BDNF, COMT, MDRI, CRH, CRF, and GC Receptor Genetic Polymorphisms With Symptomatology and Treatment Response in Psychotic Major Depression
Actual Study Start Date : October 2003
Actual Primary Completion Date : June 2012

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Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  1. You are currently experiencing symptoms that are consistent with an episode of major depression without symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
  2. You are currently experiencing symptoms that are consistent with an episode of major depression with symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
  3. You have been diagnosed with either schizophrenia or schizoaffective disorder, or
  4. You are a volunteer without a history of psychiatric illness (a healthy control subject).

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00691535


Locations
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United States, California
Stanford University School of Medicine
Stanford, California, United States, 94305
Sponsors and Collaborators
Stanford University
Investigators
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Principal Investigator: Alan F Schatzberg, MD Stanford University

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Responsible Party: Alan Schatzberg, Principle Investigator, Stanford University
ClinicalTrials.gov Identifier: NCT00691535     History of Changes
Other Study ID Numbers: SU-05132008-1160
First Posted: June 5, 2008    Key Record Dates
Last Update Posted: June 19, 2019
Last Verified: June 2019

Additional relevant MeSH terms:
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Disease
Depression
Depressive Disorder
Depressive Disorder, Major
Mental Disorders
Psychotic Disorders
Pathologic Processes
Behavioral Symptoms
Mood Disorders
Schizophrenia Spectrum and Other Psychotic Disorders