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Effective High Aerobic Intensity Endurance Training Regimes in Chronic Obstructive Pulmonary Disease (COPD) Patients

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ClinicalTrials.gov Identifier: NCT00658853
Recruitment Status : Completed
First Posted : April 15, 2008
Last Update Posted : July 18, 2016
Sponsor:
Information provided by (Responsible Party):
Norwegian University of Science and Technology

Study Description
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Brief Summary:
4 times 4 minutes interval training with and without hyperoxia is more effective than low intensity endurance training.

Condition or disease Intervention/treatment Phase
Pulmonary Disease, Chronic Obstructive Hyperoxia Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 26 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effective High Aerobic Intensity Interval Training to Improve Maximal Oxygen Uptake in COPD Patients
Study Start Date : January 2004
Actual Primary Completion Date : February 2006
Actual Study Completion Date : February 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: COPD

Arms and Interventions
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Arm Intervention/treatment
Active Comparator: 1
High aerobic intensity treadmill walking. 4 by 4 minutes interval training on a 5% graded treadmill at a heart rate corresponding to 85-95% of maximal heart rate. 3 times per week for 10 weeks.
 Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks
Active Comparator: 2
4 times 4 minutes interval training in hyperoxia - 100% oxygen
 Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks
Active Comparator: 3
One leg at a time training 4 times 4 minutes interval training using cycling ergometer
 Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks


Outcome Measures
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Primary Outcome Measures :
  1. VO2peak [ Time Frame: 10 weeks ]
  2. Ventilation [ Time Frame: 10 weeks ]
  3. FEV1 [ Time Frame: 10 weeks ]
  4. Walking performance [ Time Frame: 10 weeks ]

Secondary Outcome Measures :
  1. Quality of life [ Time Frame: 3 months ]
  2. SPSS [ Time Frame: 3 months ]

Eligibility Criteria
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Ages Eligible for Study:   20 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • COPD

Exclusion Criteria:

  • Heart disease
  • Walking or cycling inabilities
  • Other diseases
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00658853


Locations
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Norway
Norwegian University of Science and Technology
Trondheim, Norway, NO-7489
Sponsors and Collaborators
Norwegian University of Science and Technology
Investigators
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Principal Investigator: Jan Helgerud, PhD Norwegian University of Science and Technology
More Information
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Publications of Results:

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Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00658853     History of Changes
Other Study ID Numbers: 149-03
First Posted: April 15, 2008    Key Record Dates
Last Update Posted: July 18, 2016
Last Verified: July 2016
Keywords provided by Norwegian University of Science and Technology:
COPD
training
VO2peak
performance
 ventilation
high aerobic intensity treadmill walking
one leg training by cycling
Additional relevant MeSH terms:
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Lung Diseases
Pulmonary Disease, Chronic Obstructive
Hyperoxia
Respiratory Tract Diseases
 Lung Diseases, Obstructive
Signs and Symptoms, Respiratory
Signs and Symptoms