Multicenter Continuous Peripheral Nerve Block Surveillance Study (cpnb)
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ClinicalTrials.gov Identifier: NCT00653133 |
Recruitment Status :
Completed
First Posted : April 4, 2008
Results First Posted : August 19, 2013
Last Update Posted : October 2, 2018
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Postoperative Pain | Device: Ultrasound imaging Device: Peripheral nerve stimulator | Not Applicable |
Continuous peripheral nerve block techniques require the placement of catheters near target peripheral nerves. The placement of these catheters is guided by either ultrasound visualization, nerve stimulation or a combination of the two.
This surveillance study was designed to look at the rates of catheter placement related complications with the two techniques.
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 1821 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Multicenter Continuous Peripheral Nerve Block Surveillance Study Comparing Ultrasound Guided Catheter Placement to Non Ultrasound Guided Catheter Placement Techniques |
Study Start Date : | May 2007 |
Actual Primary Completion Date : | March 2009 |
Actual Study Completion Date : | March 2009 |
Arm | Intervention/treatment |
---|---|
Active Comparator: USPNB
Ultrasound imaging guided peripheral nerve block
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Device: Ultrasound imaging
Ultrasound guided techniques for placement of peripheral nerve block catheters for continuous infusion of local anesthetic |
Active Comparator: NSPNB
Peripheral nerve stimulator guided peripheral nerve block catheter placement for continuous infusion of local anesthetic
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Device: Peripheral nerve stimulator
either stimulating needle or stimulating catheter used for placement of catheter for continuous infusion of local anesthetic |
- Complications of Peripheral Nerve Block [ Time Frame: Preoperative through 3 days post operative ]Adverse events related to performance of peripheral nerve catheter placement for continuous infusion of local anesthetic

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Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Patients having elective orthopedic surgery who are candidates for CPNB as part of their management program for postoperative pain
- Age >18
- Able to give consent
Exclusion Criteria:
- Morbid obesity (BMI> 40)
- Uncooperative or having psychological or linguistic difficulties
- Previous damage to the nerve or plexus
- Significant comorbidities which the primary investigator feels would limit the quality and collection of data
- Allergy to local anesthetic agents including ropivacaine, bupivacaine and lidocaine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00653133
United States, Arizona | |
Arizona Joint and Spine | |
Chandler, Arizona, United States, 85224 | |
United States, California | |
Santa Clara Valley Medical Center | |
San Jose, California, United States, 4088855230 | |
United States, Colorado | |
Avista Adventist Hospital | |
Louisville, Colorado, United States, 80027 | |
United States, Georgia | |
Kennestone Hospital | |
Atlanta, Georgia, United States, 30060 | |
United States, Kentucky | |
The Medical Center of Bowling Green | |
Bowling Green, Kentucky, United States, 42101 | |
United States, Massachusetts | |
Caritas Good Samaritan | |
Stoughton, Massachusetts, United States, 02072 | |
United States, Mississippi | |
Wesley Medical Center | |
Hattiesburg, Mississippi, United States, 39402 | |
United States, Missouri | |
DesPeres Hospital | |
Saint Louis, Missouri, United States, 63131 | |
United States, New York | |
St. Vincents Catholic Medical Center | |
New York, New York, United States, 10011 | |
United States, North Carolina | |
Charlotte Medical Center | |
Charlotte, North Carolina, United States, 28203 | |
United States, Ohio | |
Miami Valley Hospital | |
Dayton, Ohio, United States, 45459 | |
United States, Oklahoma | |
Bailey Medical Center | |
Owasso, Oklahoma, United States, 74055 | |
United States, South Carolina | |
Roper Hospital | |
Charleston, South Carolina, United States, 29403 | |
United States, Texas | |
Memorial Herman Hospital | |
Houston, Texas, United States, 77030 | |
Titus Regional Medical Center | |
Mount Pleasant, Texas, United States, 75455 | |
United States, Virginia | |
Virginia Commonwealth University | |
Richmond, Virginia, United States, 25298 |
Principal Investigator: | Joe Rodrigo, MD | Roper Hospital, Charleston, SC |
Responsible Party: | Halyard Health |
ClinicalTrials.gov Identifier: | NCT00653133 |
Other Study ID Numbers: |
iflocpnb2007 |
First Posted: | April 4, 2008 Key Record Dates |
Results First Posted: | August 19, 2013 |
Last Update Posted: | October 2, 2018 |
Last Verified: | December 2014 |
ultrasonography peripheral nerve block peripheral nerve stimulation |
Pain, Postoperative Postoperative Complications Pathologic Processes Pain Neurologic Manifestations |