Carbon Dioxide Versus Air Insufflation in Oesophago-gastro-duodenoscopy (OGD)
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|ClinicalTrials.gov Identifier: NCT00627211|
Recruitment Status : Completed
First Posted : February 29, 2008
Last Update Posted : September 15, 2017
|Condition or disease||Intervention/treatment||Phase|
|Pain||Procedure: CO2 insufflation||Not Applicable|
To achieve a satisfactory examination of the GI tract it needs to be distended during endoscopic procedures. After the examinations many patients complain of abdominal pain and discomfort. This pain has been substantially reduced by substituting room air with CO2 in both colonoscopies and ERCPs. The use of CO2 during colonoscopy has become routine practice at many endoscopy centers.
In our study we will test the hypothesis that abdominal pain after gastroscopies also can be reduced by substituting room air with CO2.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||107 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Care Provider)|
|Official Title:||A Double-blinded, Randomized Trial Comparing Carbondioxide(CO2)and Air Insufflation in Oesophago-gastro-duodenoscopy (OGD)|
|Study Start Date :||February 2008|
|Actual Primary Completion Date :||February 2009|
|Actual Study Completion Date :||February 2009|
No Intervention: Room air insufflation
Air used for insufflation during gastroscopy to expand the lumen for inspection of the mucosal lining. This is current standard procedure, i.e. no experimental intervention.
Experimental: CO2 insufflation
CO2 used for insufflation during gastroscopy to expand the lumen for inspection of the mucosal lining. This is not standard procedure and therefore experimental intervention.
Procedure: CO2 insufflation
From the CO2 rack through the endoscopy rack CO2 will be insufflated to visualize the mucosa during oesophagogastroduodenoscopy.
- Pain after OGD [ Time Frame: 0-48 hours ]
- Pain during OGD [ Time Frame: 24 hours ]