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Potential Nosocomial Infection Prevention Via Modification of Anesthesia Intraoperative Aseptic Practice

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00617006
Recruitment Status : Completed
First Posted : February 15, 2008
Last Update Posted : February 15, 2008
Harbor Medical Inc.
Information provided by:
Dartmouth-Hitchcock Medical Center

Brief Summary:
We hypothesized that by improving hand hygiene compliance in the operative environment, we would reduce horizontal transmission of pathogenic bacteria to surgical patients.

Condition or disease
Nosocomial Infections

Detailed Description:
We performed an observational study evaluating provider adherence to these techniques. We then sought to increase hand hygiene compliance through the use of a point of care alcohol based hand hygiene device. We hypothesized that increased hand hygiene compliance would reduce bacterial contamination of the anesthesia workspace and peripheral intravenous tubing, and ultimately reducing overall morbidity and mortality secondary to a reduction in nosocomial infection rates.

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Study Type : Observational
Actual Enrollment : 114 participants
Observational Model: Ecologic or Community
Time Perspective: Prospective
Official Title: Before and After Study Evaluating Deployment of the Sprixx GJ Personal Hand Hygiene Device in the Intra-Operative Environment
Study Start Date : July 2007
Actual Primary Completion Date : August 2007
Actual Study Completion Date : October 2007

Resource links provided by the National Library of Medicine

Before (Control)
Study group representative of standard practice
After treatment group with the personal hand hygiene device ie. Device Group.

Primary Outcome Measures :
  1. The presence of a positive culture on the previously sterile patient stopcock set, and the presence of multidrug resistant bacteria [ Time Frame: Beginning and end of surgical case ]

Secondary Outcome Measures :
  1. Reduction of bacterial contamination on predetermined sites on the anesthesia machine [ Time Frame: Beginning and End of Surgical Case ]
  2. Decreased length of stay [ Time Frame: Postoperatively ]
  3. Nosocomial infection rates [ Time Frame: within 30 days postoperatively ]
  4. Mortality [ Time Frame: Within 30 days postoperatively ]

Biospecimen Retention:   Samples Without DNA
Environmental Bacterial Samples of Workspace

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Operating Rooms were randomized and patients in these rooms were enrolled for the study.

Inclusion Criteria:

  • Patients present in operating rooms randomized to study.

Exclusion Criteria:

  • Patients that were already enrolled in study and return to the operating room.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00617006

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United States, New Hampshire
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
Sponsors and Collaborators
Dartmouth-Hitchcock Medical Center
Harbor Medical Inc.
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Principal Investigator: Matthew D Koff, M.D. M.S. Dartmouth-Hitchocck Medical Center

Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Matthew D. Koff M.D. M.S./Assistant Professor Anesthesiology and Critical Care Medicine, Dartmouth-Hitchcock Medical Center Identifier: NCT00617006    
Other Study ID Numbers: CPHS# 20655
First Posted: February 15, 2008    Key Record Dates
Last Update Posted: February 15, 2008
Last Verified: February 2008
Keywords provided by Dartmouth-Hitchcock Medical Center:
Anesthesia Workspace
Hospital Acquired Infections
Hand Hygiene
Alcohol Based Cleanser
Bacterial Contamination
Additional relevant MeSH terms:
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Communicable Diseases
Cross Infection
Iatrogenic Disease
Disease Attributes
Pathologic Processes