Oral Care Protocol for Preventing Ventilator- Associated Pneumonia (VAP)
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|ClinicalTrials.gov Identifier: NCT00604916|
Recruitment Status : Completed
First Posted : January 30, 2008
Last Update Posted : January 30, 2008
The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms. Research indicates that the Gram-Negative Bacteria grows in upper air way and trachea rapidly during the initial 2-4 hospital days and the dental plague also increased dramatically at the first 5 days. About 50% cases with prolonged intubation experienced temporal swallowing disorders and majority of them recovered 7 days post weaning. Some evidence exist suggesting that oral care could reduce bacterial flora, prevent aspiration, and subsequently decrease the incidence of ventilation-associated pneumonia for this group of high risk patients.
This study aims to evaluate the effectiveness of a standardized oral care protocol in improving oral hygiene and reducing the incidence of pneumonia on a sample of surgical patients at intensive care unit.
|Condition or disease||Intervention/treatment||Phase|
|Pneumonia||Other: standardized oral care protocol - electronic toothbrush Other: mimic protocol||Early Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||53 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||The Effectiveness of an Oral Care Protocol in Preventing Ventilator- Associated Pneumonia for Intensive Care Unit Patient|
|Study Start Date :||March 2007|
|Actual Primary Completion Date :||November 2007|
|Actual Study Completion Date :||January 2008|
received a 7 day standardized oral care protocol
Other: standardized oral care protocol - electronic toothbrush
a standardized 20-minute oral care protocol using an electronic toothbrush to clean and moisturize oral cavity twice daily.
Placebo Comparator: C
received a 7 day mimic protocol
Other: mimic protocol
a mimic 20-minute protocol involving moisturizing and attention control was performed for the same intervals.
- the oral hygiene status measured by the oral assessment guide and plague index [ Time Frame: every 3~4days ]
- The incidence of VAP defined by the Clinical Pulmonary Infection Score [ Time Frame: a 7 day oral care protocol duration ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00604916
|Principal Investigator:||li-yin YAO, BSN||School of Nursing, National Taiwan University|