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Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00598949
Recruitment Status : Unknown
Verified December 2010 by Cedars-Sinai Medical Center.
Recruitment status was:  Recruiting
First Posted : January 23, 2008
Last Update Posted : December 15, 2010
Information provided by:
Cedars-Sinai Medical Center

Brief Summary:
The purpose of the study is to determine genetic links among blood-relatives and between spouses of patients with pituitary tumors.

Condition or disease
Pituitary Tumor

Detailed Description:
The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment.

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Study Type : Observational
Estimated Enrollment : 600 participants
Observational Model: Case-Control
Time Perspective: Prospective
Official Title: Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma
Study Start Date : January 2003
Estimated Primary Completion Date : December 2015

Biospecimen Retention:   Samples With DNA
cell lines are established for future genetic analysis

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
tertiary referral center

Inclusion Criteria:

  • patients harboring secretory or non-secretory adenomas and/or siblings and/or spouses

Exclusion Criteria:

  • patient without consenting siblings and/or siblings and/or spouses

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00598949

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Contact: Billy Gellepis 310-423-3395
Contact: Lori korsakoff, RN 310-423-2411

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United States, California
Cedars-Sinai Medical Center, Pituitary Center Recruiting
Los Angeles, California, United States, 90048
Contact: Vivien Bonert, MD    310-423-2830   
Contact: Lori Korsakoff, RN    310-423-2411   
Sponsors and Collaborators
Cedars-Sinai Medical Center
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Principal Investigator: Vivian Bonert, MD Cedars-Sinai Medical Center
Additional Information:
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Responsible Party: Vivien Bonert, MD, Cedars-Sinai Medical Center, Pituitary Center Identifier: NCT00598949    
Other Study ID Numbers: 3765
First Posted: January 23, 2008    Key Record Dates
Last Update Posted: December 15, 2010
Last Verified: December 2010
Keywords provided by Cedars-Sinai Medical Center:
Additional relevant MeSH terms:
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Pituitary Neoplasms
Pituitary Diseases
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Hypothalamic Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Endocrine System Diseases
Endocrine Gland Neoplasms
Neoplasms by Site
Hypothalamic Neoplasms
Supratentorial Neoplasms
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms