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The Effect Of Light On Scar Appearance

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00544635
Recruitment Status : Terminated (Study personnel left institution before study completion.)
First Posted : October 16, 2007
Last Update Posted : July 29, 2014
Information provided by:
Northwestern University

Brief Summary:
The goal of this project is to examine the ability of light exposure to improve the appearance of cutaneous scars.

Condition or disease Intervention/treatment Phase
Cutaneous Scars Device: no intervention Device: light Not Applicable

Detailed Description:
Light would be efficacious in improving scar appearance due to its known effects on wound healing, acne, and its use for skin rejuvenation. Light interacts with cells and stimulates the production of new collagen and elastin. This same energy can be used to inhibit collagen formation and help improve scars.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 50 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effect Of Light On Scar Appearance
Study Start Date : November 2005
Actual Primary Completion Date : August 2006
Actual Study Completion Date : August 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Scars

Arm Intervention/treatment
Experimental: A
scars will be treated with light
Device: light
scars will be treated with light

Placebo Comparator: B
no intervention
Device: no intervention
no intervention

Primary Outcome Measures :
  1. Scar vascularity [ Time Frame: 24 weeks ]
  2. Scar pigmentation [ Time Frame: 24 weeks ]
  3. Scar thickness [ Time Frame: 24 weeks ]
  4. Scar length [ Time Frame: 24 weeks ]
  5. Scar width [ Time Frame: 24 weeks ]
  6. Scar surface area [ Time Frame: 24 weeks ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Have two lesions that have been selected for excision
  • Have two cutaneous scars from previous excisions as part of a standard of care
  • Subjects are in good health
  • Subject has a willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator

Exclusion Criteria:

  • Pregnancy or lactation
  • Subjects who are unable to understand the protocol or to give informed consent
  • Subjects with mental illness

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00544635

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United States, Illinois
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
Northwestern University
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Principal Investigator: Murad Alam, MD Northwestern University
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Responsible Party: Murad Alam, MD, Northwestern University Identifier: NCT00544635    
Other Study ID Numbers: 1253-010
First Posted: October 16, 2007    Key Record Dates
Last Update Posted: July 29, 2014
Last Verified: July 2014
Additional relevant MeSH terms:
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Pathologic Processes